Polymicrobial cholangitis and kaposi's sarcoma in blood product transfusion-related acquired immune deficiency syndrome

Franklin R. Cockerill, Dominic V. Hurley, Juan R. Malagelada, Nicholas F. Larusso, Randall S. Edson, Jerry A. Katzmann, Peter M. Banks, John C. Wiltsie, Jeffrey P. Davis, Ernest E. Lack, Kamil G. Ishak, Robert E. Van Scoy

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29 Scopus citations

Abstract

Before presenting to the Mayo Clinic, a 24-year-old white woman had received 35 transfusions of blood products over a 72-hour period in February 1981. Two and one half years later, the diagnosis of polymicrobial cholangitis (Cryptosporidium, Candida albicans, and Klebsiella pneumoniae) was established. Further evaluation demonstrated profound helper T lymphocyte suppression, disseminated Mycobacterium avium-intracellulare infection with. mycobacteremia, and Kaposi's sarcoma of lymphoid tissue, confirming a diagnosis of acquired immune deficiency syndrome (AIDS). This case represents an unusual infectious complication of AIDS. Additionally, this is believed to be the first report of Kaposi's sarcoma occurring in a patient with AIDS associated with blood product transfusion.

Original languageEnglish (US)
Pages (from-to)1237-1241
Number of pages5
JournalThe American Journal of Medicine
Volume80
Issue number6
DOIs
StatePublished - Jun 1986

ASJC Scopus subject areas

  • Medicine(all)

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    Cockerill, F. R., Hurley, D. V., Malagelada, J. R., Larusso, N. F., Edson, R. S., Katzmann, J. A., Banks, P. M., Wiltsie, J. C., Davis, J. P., Lack, E. E., Ishak, K. G., & Van Scoy, R. E. (1986). Polymicrobial cholangitis and kaposi's sarcoma in blood product transfusion-related acquired immune deficiency syndrome. The American Journal of Medicine, 80(6), 1237-1241. https://doi.org/10.1016/0002-9343(86)90695-9