Polyarteritis nodosa: Spectrum of angiographic findings

Anthony W. Stanson, Jeremy L. Friese, C. Michael Johnson, Michael A. McKusick, Jerome F. Breen, Enrique A. Sabater, James C. Andrews

Research output: Contribution to journalArticle

94 Scopus citations

Abstract

The purpose of this study was to review the positive angiographic findings in patients with polyarteritis nodosa (PAN). The authors reviewed the angiograms of 56 consecutive patients (25 women and 31 men; age range, 18-81 years; mean age, 55 years) with PAN and arterial abnormalities consistent with necrotizing vasculitis. Aneurysms were present in 27 patients and segments of ectasia were present in seven patients, for a total of 34 (61%) of 56 patients with aneurysmal lesions. The remaining 22 (39%) patients had arterial lesions that were occlusive: luminal irregularity, stenosis, or occlusion. All but one of the patients with an aneurysm also had occlusive lesions. Therefore, 55 (98%) of the 56 patients were found to have occlusive lesions. Skeletal muscle arteries were affected in 18 patients, nine in the extremities. The most frequent finding in patients with PAN was occlusive arterial lesions. Although the presence of aneurysms increases specificity for the diagnosis of PAN, many patients have only occlusive lesions. Involvement of skeletal muscle arteries was common.

Original languageEnglish (US)
Pages (from-to)151-159
Number of pages9
JournalRadiographics
Volume21
Issue number1
DOIs
StatePublished - 2001

Keywords

  • Arteries, splenic, 954.621
  • Arteries, superior mesenteric, 955.621
  • Arteritis, 621
  • Hepatic arteries, 952.621
  • Renal arteries, 961.621

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Stanson, A. W., Friese, J. L., Johnson, C. M., McKusick, M. A., Breen, J. F., Sabater, E. A., & Andrews, J. C. (2001). Polyarteritis nodosa: Spectrum of angiographic findings. Radiographics, 21(1), 151-159. https://doi.org/10.1148/radiographics.21.1.g01ja16151