Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application

Robert C. Thomson, Michael J Yaszemski, John M. Powers, Timothy P. Harrigan, Antonios G. Mikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

A process has been developed to manufacture biodegradable composite foams of poly(DL-lactic-co-glycolic acid) (PLGA) and hydroxyapatite short fibers for use in bone regeneration. The technique allows the manufacture of 3D foam scaffolds and involves the formation of a composite material consisting of a porogen material and hydroxyapatite short fibers embedded in a PLGA matrix. The porogen is initially leached out, then an opencell composite foam remains, which has a pore size and morphology defined by the porogen. The foam porosity can be controlled by altering the volume fraction of the porogen used to make the composite material. The foams are made using various porogen materials. The composite foams may be expected to enhance osteoconductivity and hence provide a novel material that may be useful in the field of bone regeneration.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium - Proceedings
PublisherMaterials Research Society
Pages25-30
Number of pages6
Volume394
StatePublished - 1995
Externally publishedYes
EventProceedings of the 1995 MRS Spring Meeting - San Francisco, CA, USA
Duration: Apr 17 1995Apr 21 1995

Other

OtherProceedings of the 1995 MRS Spring Meeting
CitySan Francisco, CA, USA
Period4/17/954/21/95

Fingerprint

Orthopedics
Durapatite
Hydroxyapatite
Foams
Esters
glycolic acid
Fibers
Composite materials
Bone
Acids
Scaffolds
Pore size
Volume fraction
Porosity

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Thomson, R. C., Yaszemski, M. J., Powers, J. M., Harrigan, T. P., & Mikos, A. G. (1995). Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application. In Materials Research Society Symposium - Proceedings (Vol. 394, pp. 25-30). Materials Research Society.

Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application. / Thomson, Robert C.; Yaszemski, Michael J; Powers, John M.; Harrigan, Timothy P.; Mikos, Antonios G.

Materials Research Society Symposium - Proceedings. Vol. 394 Materials Research Society, 1995. p. 25-30.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Thomson, RC, Yaszemski, MJ, Powers, JM, Harrigan, TP & Mikos, AG 1995, Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application. in Materials Research Society Symposium - Proceedings. vol. 394, Materials Research Society, pp. 25-30, Proceedings of the 1995 MRS Spring Meeting, San Francisco, CA, USA, 4/17/95.
Thomson RC, Yaszemski MJ, Powers JM, Harrigan TP, Mikos AG. Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application. In Materials Research Society Symposium - Proceedings. Vol. 394. Materials Research Society. 1995. p. 25-30
Thomson, Robert C. ; Yaszemski, Michael J ; Powers, John M. ; Harrigan, Timothy P. ; Mikos, Antonios G. / Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application. Materials Research Society Symposium - Proceedings. Vol. 394 Materials Research Society, 1995. pp. 25-30
@inproceedings{3f1132cb189d4f6d9fe4ecd014a6463f,
title = "Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application",
abstract = "A process has been developed to manufacture biodegradable composite foams of poly(DL-lactic-co-glycolic acid) (PLGA) and hydroxyapatite short fibers for use in bone regeneration. The technique allows the manufacture of 3D foam scaffolds and involves the formation of a composite material consisting of a porogen material and hydroxyapatite short fibers embedded in a PLGA matrix. The porogen is initially leached out, then an opencell composite foam remains, which has a pore size and morphology defined by the porogen. The foam porosity can be controlled by altering the volume fraction of the porogen used to make the composite material. The foams are made using various porogen materials. The composite foams may be expected to enhance osteoconductivity and hence provide a novel material that may be useful in the field of bone regeneration.",
author = "Thomson, {Robert C.} and Yaszemski, {Michael J} and Powers, {John M.} and Harrigan, {Timothy P.} and Mikos, {Antonios G.}",
year = "1995",
language = "English (US)",
volume = "394",
pages = "25--30",
booktitle = "Materials Research Society Symposium - Proceedings",
publisher = "Materials Research Society",

}

TY - GEN

T1 - Poly(α-hydroxy ester)/short fiber hydroxyapatite composite foams for orthopedic application

AU - Thomson, Robert C.

AU - Yaszemski, Michael J

AU - Powers, John M.

AU - Harrigan, Timothy P.

AU - Mikos, Antonios G.

PY - 1995

Y1 - 1995

N2 - A process has been developed to manufacture biodegradable composite foams of poly(DL-lactic-co-glycolic acid) (PLGA) and hydroxyapatite short fibers for use in bone regeneration. The technique allows the manufacture of 3D foam scaffolds and involves the formation of a composite material consisting of a porogen material and hydroxyapatite short fibers embedded in a PLGA matrix. The porogen is initially leached out, then an opencell composite foam remains, which has a pore size and morphology defined by the porogen. The foam porosity can be controlled by altering the volume fraction of the porogen used to make the composite material. The foams are made using various porogen materials. The composite foams may be expected to enhance osteoconductivity and hence provide a novel material that may be useful in the field of bone regeneration.

AB - A process has been developed to manufacture biodegradable composite foams of poly(DL-lactic-co-glycolic acid) (PLGA) and hydroxyapatite short fibers for use in bone regeneration. The technique allows the manufacture of 3D foam scaffolds and involves the formation of a composite material consisting of a porogen material and hydroxyapatite short fibers embedded in a PLGA matrix. The porogen is initially leached out, then an opencell composite foam remains, which has a pore size and morphology defined by the porogen. The foam porosity can be controlled by altering the volume fraction of the porogen used to make the composite material. The foams are made using various porogen materials. The composite foams may be expected to enhance osteoconductivity and hence provide a novel material that may be useful in the field of bone regeneration.

UR - http://www.scopus.com/inward/record.url?scp=0029474489&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029474489&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0029474489

VL - 394

SP - 25

EP - 30

BT - Materials Research Society Symposium - Proceedings

PB - Materials Research Society

ER -