Pneumonia: Treatment and diagnosis

Joshua T. Mattila, Michael J. Fine, Andrew Harold Limper, Patrick R. Murray, Bill B. Chen, Philana Ling Lin

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Pneumonia remains a leading cause of morbidity and mortality despite advances in treatment and therapy. The "Pneumonia: Treatment and Diagnosis " session of the Pittsburgh International Lung Conference examined topics related to improving care of patients with pneumonia. These topics included the process and quality of care for community-acquired pneumonia (CAP), diagnosis and treatment of emerging fungal pathogens, an overview of the strengths and weaknesses of different diagnostic modalities, and an example of how basic science is exploring immunomodulatory strategies for pneumonia treatment. Systematic health care provider and institutional improvements can decrease mortality rates in CAP, particularly in patients with increasingly complex comorbidities. Aspects of current guidelines for the diagnosis and treatment of fungal pneumonia were reviewed through a series of case presentations. Proper treatment of pneumonia hinges on correct pathogen identi fication but is complicated by the variety of diagnostic assays with variable specificity, sensitivity, and interpretation. In addressing this topic, Dr. Patrick Murray, Ph.D., discussed a range of diagnostic tests for a variety of pathogens and guidelines for their use. In addition to the current state of CAP treatment, Bill (Beibei) Chen, M.D., Ph.D., presented a new potential therapeutic agent called forsythin, an immunomodulatory compound derived from a plant used in traditional Chinese medicine. These topics, ranging from institution-sized policy to interactions at the molecular scale, paint a broad perspective of the efforts against pneumonia.

Original languageEnglish (US)
Pages (from-to)S189-S192
JournalAnnals of the American Thoracic Society
Volume11
DOIs
StatePublished - Aug 1 2014

Fingerprint

Pneumonia
Therapeutics
Guidelines
Paint
Mortality
Quality of Health Care
Chinese Traditional Medicine
Phytochemicals
Routine Diagnostic Tests
Health Personnel
Comorbidity
Patient Care
Morbidity
Sensitivity and Specificity
Lung

Keywords

  • Community-acquired infections
  • Diagnostic techniques and procedures
  • Health care quality, access, and evaluation
  • Inflammation mediators
  • Mycoses

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Mattila, J. T., Fine, M. J., Limper, A. H., Murray, P. R., Chen, B. B., & Lin, P. L. (2014). Pneumonia: Treatment and diagnosis. Annals of the American Thoracic Society, 11, S189-S192. https://doi.org/10.1513/AnnalsATS.201401-027PL

Pneumonia : Treatment and diagnosis. / Mattila, Joshua T.; Fine, Michael J.; Limper, Andrew Harold; Murray, Patrick R.; Chen, Bill B.; Lin, Philana Ling.

In: Annals of the American Thoracic Society, Vol. 11, 01.08.2014, p. S189-S192.

Research output: Contribution to journalArticle

Mattila, JT, Fine, MJ, Limper, AH, Murray, PR, Chen, BB & Lin, PL 2014, 'Pneumonia: Treatment and diagnosis', Annals of the American Thoracic Society, vol. 11, pp. S189-S192. https://doi.org/10.1513/AnnalsATS.201401-027PL
Mattila, Joshua T. ; Fine, Michael J. ; Limper, Andrew Harold ; Murray, Patrick R. ; Chen, Bill B. ; Lin, Philana Ling. / Pneumonia : Treatment and diagnosis. In: Annals of the American Thoracic Society. 2014 ; Vol. 11. pp. S189-S192.
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