Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young

Research output: Contribution to journalReview article

Abstract

Purpose: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or young adult population. The imaging features of PLNTY are not well characterized in the existing literature. Methods: We performed a retrospective review, identifying nine patients with pathologically proven PLNTY and available preoperative imaging in order to identify common features which may facilitate confident imaging diagnosis of this entity. Results: Patients were ages 5 to 34 years (median 16 years), and seven (78%) were female. Most tumors had a highly characteristic appearance, with temporal lobe location (6/9; 67%), calcification (8/9; 89%), cortical/subcortical origin (8/9; 89%), cystic components (8/9; 89%), and relatively infrequent contrast enhancement (3/9; 33%). Conclusion: PLNTYs demonstrate characteristic calcification, subcortical location, and frequent temporal lobe localization, features that may allow radiologists to prospectively suggest the diagnosis in the proper clinical setting.

Original languageEnglish (US)
JournalNeuroradiology
DOIs
StateAccepted/In press - Jan 1 2019

Fingerprint

Neuroepithelial Neoplasms
Temporal Lobe
Neoplasms
Names
Young Adult
Pediatrics
Population

Keywords

  • Brain tumor
  • Calcification
  • CT
  • Pediatric
  • PLNTY
  • Polymorphous low-grade neuroepithelial tumor of the young

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

@article{2b4e28d0a8d3498db462cd77504e0dd1,
title = "Plenty of calcification: imaging characterization of polymorphous low-grade neuroepithelial tumor of the young",
abstract = "Purpose: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or young adult population. The imaging features of PLNTY are not well characterized in the existing literature. Methods: We performed a retrospective review, identifying nine patients with pathologically proven PLNTY and available preoperative imaging in order to identify common features which may facilitate confident imaging diagnosis of this entity. Results: Patients were ages 5 to 34 years (median 16 years), and seven (78{\%}) were female. Most tumors had a highly characteristic appearance, with temporal lobe location (6/9; 67{\%}), calcification (8/9; 89{\%}), cortical/subcortical origin (8/9; 89{\%}), cystic components (8/9; 89{\%}), and relatively infrequent contrast enhancement (3/9; 33{\%}). Conclusion: PLNTYs demonstrate characteristic calcification, subcortical location, and frequent temporal lobe localization, features that may allow radiologists to prospectively suggest the diagnosis in the proper clinical setting.",
keywords = "Brain tumor, Calcification, CT, Pediatric, PLNTY, Polymorphous low-grade neuroepithelial tumor of the young",
author = "Johnson, {Derek R.} and Caterina Giannini and Jenkins, {Robert Brian} and Kim, {Dong Kun} and Kaufmann, {Timothy J}",
year = "2019",
month = "1",
day = "1",
doi = "10.1007/s00234-019-02269-y",
language = "English (US)",
journal = "Neuroradiology",
issn = "0028-3940",
publisher = "Springer Verlag",

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TY - JOUR

T1 - Plenty of calcification

T2 - imaging characterization of polymorphous low-grade neuroepithelial tumor of the young

AU - Johnson, Derek R.

AU - Giannini, Caterina

AU - Jenkins, Robert Brian

AU - Kim, Dong Kun

AU - Kaufmann, Timothy J

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Purpose: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or young adult population. The imaging features of PLNTY are not well characterized in the existing literature. Methods: We performed a retrospective review, identifying nine patients with pathologically proven PLNTY and available preoperative imaging in order to identify common features which may facilitate confident imaging diagnosis of this entity. Results: Patients were ages 5 to 34 years (median 16 years), and seven (78%) were female. Most tumors had a highly characteristic appearance, with temporal lobe location (6/9; 67%), calcification (8/9; 89%), cortical/subcortical origin (8/9; 89%), cystic components (8/9; 89%), and relatively infrequent contrast enhancement (3/9; 33%). Conclusion: PLNTYs demonstrate characteristic calcification, subcortical location, and frequent temporal lobe localization, features that may allow radiologists to prospectively suggest the diagnosis in the proper clinical setting.

AB - Purpose: Polymorphous low-grade neuroepithelial tumor of the young (PLNTY) is a recently described epileptogenic neoplasm. As the name implies, PLNTYs are indolent tumors most often encountered in the pediatric or young adult population. The imaging features of PLNTY are not well characterized in the existing literature. Methods: We performed a retrospective review, identifying nine patients with pathologically proven PLNTY and available preoperative imaging in order to identify common features which may facilitate confident imaging diagnosis of this entity. Results: Patients were ages 5 to 34 years (median 16 years), and seven (78%) were female. Most tumors had a highly characteristic appearance, with temporal lobe location (6/9; 67%), calcification (8/9; 89%), cortical/subcortical origin (8/9; 89%), cystic components (8/9; 89%), and relatively infrequent contrast enhancement (3/9; 33%). Conclusion: PLNTYs demonstrate characteristic calcification, subcortical location, and frequent temporal lobe localization, features that may allow radiologists to prospectively suggest the diagnosis in the proper clinical setting.

KW - Brain tumor

KW - Calcification

KW - CT

KW - Pediatric

KW - PLNTY

KW - Polymorphous low-grade neuroepithelial tumor of the young

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