TY - JOUR
T1 - Platypnea-orthodeoxia syndrome
T2 - Diagnostic challenge and the importance of heightened clinical suspicion
AU - Henkin, Stanislav
AU - Negrotto, Sara
AU - Pollak, Peter M.
AU - Cullen, Michael W.
AU - O’Cochlain, D. Fearghas
AU - Scott Wright, R.
N1 - Publisher Copyright:
© 2015 by the Texas Heart ® Institute, Houston.
PY - 2015/10
Y1 - 2015/10
N2 - Platypnea-orthodeoxia syndrome is an uncommon condition of positional dyspnea and hypoxemia; symptoms occur when the patient is upright and resolve with recumbency. Causes can be broadly categorized into 4 groups: intracardiac shunting, pulmonary shunting, ventilation-perfusion mismatch, or a combination of these. Platypnea-orthodeoxia syndrome should be suspected when normal arterial oxygen saturations are recorded while an individual is supine, followed by abrupt declines in those saturations when upright. Further investigations with use of imaging and cardiac catheterization aid in the evaluation. When platypnea-orthodeoxia syndrome is due to intracardiac shunting without pulmonary hypertension, intracardiac shunt closure can be curative. In this article, we report a case of platypnea-orthodeoxia syndrome in an 83-year-old woman who was successfully treated by means of percutaneous transcatheter closure of an atrial septal defect.
AB - Platypnea-orthodeoxia syndrome is an uncommon condition of positional dyspnea and hypoxemia; symptoms occur when the patient is upright and resolve with recumbency. Causes can be broadly categorized into 4 groups: intracardiac shunting, pulmonary shunting, ventilation-perfusion mismatch, or a combination of these. Platypnea-orthodeoxia syndrome should be suspected when normal arterial oxygen saturations are recorded while an individual is supine, followed by abrupt declines in those saturations when upright. Further investigations with use of imaging and cardiac catheterization aid in the evaluation. When platypnea-orthodeoxia syndrome is due to intracardiac shunting without pulmonary hypertension, intracardiac shunt closure can be curative. In this article, we report a case of platypnea-orthodeoxia syndrome in an 83-year-old woman who was successfully treated by means of percutaneous transcatheter closure of an atrial septal defect.
KW - Aged, 80 and over
KW - Atrial septal defect
KW - Cardiac platypnea-orthodeoxia syndrome
KW - Dyspnea/etiology/physiopathology
KW - Foramen ovale, patent
KW - Heart septal defects, atrial/complications
KW - Oxygen/blood
KW - Posture/physiology
KW - Septal occluder device
KW - Supine position
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U2 - 10.14503/THIJ-14-4596
DO - 10.14503/THIJ-14-4596
M3 - Article
C2 - 26504452
AN - SCOPUS:84943274901
SN - 0730-2347
VL - 42
SP - 498
EP - 501
JO - Texas Heart Institute Journal
JF - Texas Heart Institute Journal
IS - 5
ER -