Platelets in the pathogenesis of acute respiratory distress syndrome

Hemang Yadav, Daryl J. Kor

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations

Abstract

Platelets have an emerging and incompletely understood role in a myriad of host immune responses, extending their role well beyond regulating thrombosis. Acute respiratory distress syndrome is a complex disease process characterized by a range of pathophysiologic processes including oxidative stress, lung deformation, inflammation, and intravascular coagulation. The objective of this review is to summarize existing knowledge on platelets and their putative role in the development and resolution of lung injury.

Original languageEnglish (US)
Pages (from-to)L915-L923
JournalAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
Volume309
Issue number9
DOIs
StatePublished - 2015

Keywords

  • ALI
  • ARDS
  • Aspirin
  • Lung injury
  • Platelet

ASJC Scopus subject areas

  • Physiology
  • Pulmonary and Respiratory Medicine
  • Physiology (medical)
  • Cell Biology

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