Platelet activity and outcome after intracerebral hemorrhage

Andrew M. Naidech, Richard A. Bernstein, Kimberly Levasseur, Sarice L. Bassin, Bernard R. Bendok, H. Hunt Batjer, Thomas P. Bleck, Mark J. Alberts

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.

Original languageEnglish (US)
Pages (from-to)352-356
Number of pages5
JournalAnnals of neurology
Volume65
Issue number3
DOIs
StatePublished - Mar 1 2009

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    Naidech, A. M., Bernstein, R. A., Levasseur, K., Bassin, S. L., Bendok, B. R., Batjer, H. H., Bleck, T. P., & Alberts, M. J. (2009). Platelet activity and outcome after intracerebral hemorrhage. Annals of neurology, 65(3), 352-356. https://doi.org/10.1002/ana.21618