Platelet activity and outcome after intracerebral hemorrhage

Andrew M. Naidech, Richard A. Bernstein, Kimberly Levasseur, Sarice L. Bassin, Bernard Bendok, H. Hunt Batjer, Thomas P. Bleck, Mark J. Alberts

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

There are few data on platelet function in intracerebral hemorrhage (ICH). We prospectively enrolled 69 patients with ICH and measured platelet function on admission. Aspirin use before ICH was associated with reduced platelet activity. Less platelet activity was associated with intraventricular hemorrhage (516.5 [interquartile range (IQR), 454-629.25] vs 637 [IQR, 493-654] aspirin reaction units; p = 0.04) and death at 14 days (480.5 [IQR, 444.5-632.5] vs 626 [IQR, 494-652] aspirin reaction units; p = 0.04). Objective measures of platelet function on admission are associated with intraventricular hemorrhage and death after ICH.

Original languageEnglish (US)
Pages (from-to)352-356
Number of pages5
JournalAnnals of Neurology
Volume65
Issue number3
DOIs
StatePublished - Mar 2009
Externally publishedYes

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Cerebral Hemorrhage
Blood Platelets
Aspirin
Hemorrhage

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Naidech, A. M., Bernstein, R. A., Levasseur, K., Bassin, S. L., Bendok, B., Batjer, H. H., ... Alberts, M. J. (2009). Platelet activity and outcome after intracerebral hemorrhage. Annals of Neurology, 65(3), 352-356. https://doi.org/10.1002/ana.21618

Platelet activity and outcome after intracerebral hemorrhage. / Naidech, Andrew M.; Bernstein, Richard A.; Levasseur, Kimberly; Bassin, Sarice L.; Bendok, Bernard; Batjer, H. Hunt; Bleck, Thomas P.; Alberts, Mark J.

In: Annals of Neurology, Vol. 65, No. 3, 03.2009, p. 352-356.

Research output: Contribution to journalArticle

Naidech, AM, Bernstein, RA, Levasseur, K, Bassin, SL, Bendok, B, Batjer, HH, Bleck, TP & Alberts, MJ 2009, 'Platelet activity and outcome after intracerebral hemorrhage', Annals of Neurology, vol. 65, no. 3, pp. 352-356. https://doi.org/10.1002/ana.21618
Naidech AM, Bernstein RA, Levasseur K, Bassin SL, Bendok B, Batjer HH et al. Platelet activity and outcome after intracerebral hemorrhage. Annals of Neurology. 2009 Mar;65(3):352-356. https://doi.org/10.1002/ana.21618
Naidech, Andrew M. ; Bernstein, Richard A. ; Levasseur, Kimberly ; Bassin, Sarice L. ; Bendok, Bernard ; Batjer, H. Hunt ; Bleck, Thomas P. ; Alberts, Mark J. / Platelet activity and outcome after intracerebral hemorrhage. In: Annals of Neurology. 2009 ; Vol. 65, No. 3. pp. 352-356.
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