Plasmaperfusion and studies of copper metabolism in benign recurrent cholestasis. Novel procedures in a rare syndrome

A 21-year-old woman with recurrent episodes of pruritus and jaundice since childhood was diagnosed as having benign recurrent cholestasis, a rare and poorly understood disease. Plasmaperfusion was successfully employed for therapy of the severe pruritus, and various studies of copper metabolism were performed in an attempt to clarify the pathophysiology of this obscure syndrome.