Plasma Cell Leukemia and Extramedullary Plasmacytoma

Morie Gertz; Laura Rosinol; Joan Bladé

doi:10.1007/978-3-319-25586-6_9

Plasma Cell Leukemia and Extramedullary Plasmacytoma

Morie Gertz, Laura Rosinol, Joan Bladé

Hematology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Plasma cell leukemia represents a unique subset of patients with multiple myeloma. The operational definition requires that the patient have a blood leukocyte count >10,000 and at least 2000 circulating plasma cells. This also must constitute 20% of circulating cells. Plasma cell leukemia is classified as primary when the initial diagnosis is with circulating cells and secondary when it occurs at the time of relapse. Extramedullary plasmacytomas can be either outside of the cortical bone or extension from the cortical bone and represent a high-risk form of multiple myeloma. This book chapter deals with the natural history, biology, clinical outcomes, and therapy of these two uncommon manifestations of multiple myeloma.

Original language	English (US)
Title of host publication	Hematologic Malignancies
Publisher	Springer Verlag
Pages	157-175
Number of pages	19
Edition	9783319255842
DOIs	https://doi.org/10.1007/978-3-319-25586-6_9
State	Published - Jan 1 2018

Publication series

Name	Hematologic Malignancies
Number	9783319255842
ISSN (Print)	2197-9766
ISSN (Electronic)	2197-9774

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Keywords

Extramedullary myeloma
High risk myeloma
Plasma cell leukemia
Solitary plasmacytoma

ASJC Scopus subject areas

Hematology
Oncology

Cite this

Gertz, M., Rosinol, L., & Bladé, J. (2018). Plasma Cell Leukemia and Extramedullary Plasmacytoma. In Hematologic Malignancies (9783319255842 ed., pp. 157-175). (Hematologic Malignancies; No. 9783319255842). Springer Verlag. https://doi.org/10.1007/978-3-319-25586-6_9

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Access to Document

10.1007/978-3-319-25586-6_9