By postmortem biochemical and molecular genetic analyses, an 8-month-old infant was diagnosed with long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency, an inborn error of mitochondrial fatty acid β-oxidation. He was born following a pregnancy complicated by a maternal floor infarction of the placenta, a disorder of unknown etiology. We speculate that the child's autosomal recessive fatty acid β-oxidation disorder and the pregnancy complication are causally related.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Molecular Biology