Pituitary adenoma with tumoral granulomatous reaction

Bernd W. Scheithauer, Ana Isabel Silva, John L D Atkinson, Todd B. Nippoldt, Timothy J Kaufmann, Kalman Kovacs, Eva Horvath, Ricardo Lloyd

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Herein, we report a unique case of an adult male with a corticotrophic pituitary adenoma of silent subtype 1 exhibiting conspicuous idiopathic tumoral noncaseating granulomatous inflammation. The lesion was unassociated with clinical or laboratory evidence of either systemic sarcoidosis or infection. Histochemical and polymerase chain reaction (PCR) studies revealed neither fungi nor tubercle bacilli. We suggest that tumoral production of an as yet uncharacterized antigen may have induced the granulomatous inflammatory reaction.

Original languageEnglish (US)
Pages (from-to)86-90
Number of pages5
JournalEndocrine Pathology
Volume18
Issue number2
DOIs
StatePublished - Jun 2007

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Pituitary Neoplasms
Sarcoidosis
Bacillus
Fungi
Inflammation
Antigens
Polymerase Chain Reaction
Infection

Keywords

  • Granuloma
  • Inflammation
  • Pituitary
  • Silent corticotroph adenoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Scheithauer, B. W., Silva, A. I., Atkinson, J. L. D., Nippoldt, T. B., Kaufmann, T. J., Kovacs, K., ... Lloyd, R. (2007). Pituitary adenoma with tumoral granulomatous reaction. Endocrine Pathology, 18(2), 86-90. https://doi.org/10.1007/s12022-007-0017-5

Pituitary adenoma with tumoral granulomatous reaction. / Scheithauer, Bernd W.; Silva, Ana Isabel; Atkinson, John L D; Nippoldt, Todd B.; Kaufmann, Timothy J; Kovacs, Kalman; Horvath, Eva; Lloyd, Ricardo.

In: Endocrine Pathology, Vol. 18, No. 2, 06.2007, p. 86-90.

Research output: Contribution to journalArticle

Scheithauer, BW, Silva, AI, Atkinson, JLD, Nippoldt, TB, Kaufmann, TJ, Kovacs, K, Horvath, E & Lloyd, R 2007, 'Pituitary adenoma with tumoral granulomatous reaction', Endocrine Pathology, vol. 18, no. 2, pp. 86-90. https://doi.org/10.1007/s12022-007-0017-5
Scheithauer BW, Silva AI, Atkinson JLD, Nippoldt TB, Kaufmann TJ, Kovacs K et al. Pituitary adenoma with tumoral granulomatous reaction. Endocrine Pathology. 2007 Jun;18(2):86-90. https://doi.org/10.1007/s12022-007-0017-5
Scheithauer, Bernd W. ; Silva, Ana Isabel ; Atkinson, John L D ; Nippoldt, Todd B. ; Kaufmann, Timothy J ; Kovacs, Kalman ; Horvath, Eva ; Lloyd, Ricardo. / Pituitary adenoma with tumoral granulomatous reaction. In: Endocrine Pathology. 2007 ; Vol. 18, No. 2. pp. 86-90.
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