Pitfall of 18 F-FDG PET/CT in characterization of relapsed multisystem lymphomatoid granulomatosis

Kelly Tung, Allison C. Rosenthal, Fiona E. Craig, Jonathan B. Ashman, Ming Yang

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We present serial 18 F-FDG PET/CT findings in a case of grade 3 pulmonary lymphomatoid granulomatosis positive for the Epstein-Barr virus. The patient experienced a transient complete response to R-CHOP chemotherapy and subsequent multisystem recurrence, predominately involving the subcutaneous region of the torso on 18 F-FDG PET/CT. Biopsy of the most hypermetabolic subcutaneous lesion demonstrated grade 1 cutaneous lymphomatoid granulomatosis negative for the Epstein-Barr virus. This report highlights the role of 18 F-FDG PET/CT in characterizing and monitoring disease progression and regression, as well as the limitations of 18 F-FDG PET/CT in accurate grading of multisystem recurrence, given the diversity of clinical and histopathologic features of lymphomatoid granulomatosis.

Original languageEnglish (US)
Pages (from-to)396-397
Number of pages2
JournalJournal of nuclear medicine technology
Volume46
Issue number4
DOIs
StatePublished - Dec 1 2018

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Keywords

  • F-FDG
  • Hematology
  • Lung
  • Lymphoma
  • Lymphomatoid granulomatosis
  • PET/CT

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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