Pilot study of detection, radiologist confidence and image quality with sinogram-affirmed iterative reconstruction at half-routine dose level

Joel Garland Fletcher, William R. Krueger, David M. Hough, James E. Huprich, Jeff L. Fidler, Jia Wang, Maria M. Shiung, W. Scott Harmsen, Katharine L. Grant, Cynthia H McCollough

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

OBJECTIVE: The objective of this study was to determine the effect of Sinogram-Affirmed Iterative Reconstruction (SAFIRE) on radiological detection, diagnostic confidence, and image quality at half-dose, contrast-enhanced abdominopelvic computed tomography. METHODS: Forty dual-source examinations were reconstructed using routine-dose with filtered back projection, half-dose filtered back projection, and half-dose SAFIRE. Three radiologists detected lesions in abdominopelvic organs, reporting findings of potential medical significance, diagnostic confidence, and image quality. RESULTS: There was greater than 78% concordance between full- and half-dose images ± SAFIRE, and no difference in the detection of lesions within organs between half-dose images ± SAFIRE (P = 0.22 - 1.0). Detection of potentially important findings varied by reader, but not between dose/reconstruction methods. Diagnostic confidence varied widely (P < 0.001 to P > 0.91). Sinogram-Affirmed Iterative Reconstruction significantly improved image quality in the pelvis (P ≤ 0.04). CONCLUSIONS: Half-dose images ± SAFIRE had organ-specific detections similar to routine-dose images. Sinogram-Affirmed Iterative Reconstruction improved image quality in the pelvis, but diagnostic confidence and image quality scores in the abdomen depended on the reader.

Original languageEnglish (US)
Pages (from-to)203-211
Number of pages9
JournalJournal of Computer Assisted Tomography
Volume37
Issue number2
DOIs
StatePublished - Mar 2013

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Pelvis
Computer-Assisted Image Processing
Abdomen
Tomography
Radiologists

Keywords

  • CT
  • Image enhancement
  • Observer variation
  • Radiation dosage

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Pilot study of detection, radiologist confidence and image quality with sinogram-affirmed iterative reconstruction at half-routine dose level. / Fletcher, Joel Garland; Krueger, William R.; Hough, David M.; Huprich, James E.; Fidler, Jeff L.; Wang, Jia; Shiung, Maria M.; Harmsen, W. Scott; Grant, Katharine L.; McCollough, Cynthia H.

In: Journal of Computer Assisted Tomography, Vol. 37, No. 2, 03.2013, p. 203-211.

Research output: Contribution to journalArticle

Fletcher, Joel Garland ; Krueger, William R. ; Hough, David M. ; Huprich, James E. ; Fidler, Jeff L. ; Wang, Jia ; Shiung, Maria M. ; Harmsen, W. Scott ; Grant, Katharine L. ; McCollough, Cynthia H. / Pilot study of detection, radiologist confidence and image quality with sinogram-affirmed iterative reconstruction at half-routine dose level. In: Journal of Computer Assisted Tomography. 2013 ; Vol. 37, No. 2. pp. 203-211.
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AU - Fidler, Jeff L.

AU - Wang, Jia

AU - Shiung, Maria M.

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