TY - JOUR
T1 - Pilocytic Astrocytomas
T2 - Well-Demarcated Magnetic Resonance Appearance Despite Frequent Infiltration Histologically
AU - Coakley, Kevin J.
AU - Huston, John
AU - Scheithauer, Bernd W.
AU - Forbes, Glenn
AU - Kelly, Patrick J.
PY - 1995
Y1 - 1995
N2 - To determine the magnetic resonance imaging (MRI) characteristics of pilocytic astro-cytomas and to correlate them with the histopathologic findings. MRI examinations and histopathologic findings in 56 patients with pilocytic astrocytomas were retrospectively reviewed. In 38 patients, findings on MRI were compared with those on computed tomography. The tumors occurred at all levels of the central nervous system, including the spinal cord. The intracranial tumors were periventricular (73%) or periaqueductal (9%). All tumors were typical pilocytic astrocytomas and were grade 1 on the basis of the World Health Organization classification. At operation, they were often circumscribed and cystic. Radiologically, the tumors were well demarcated (96%), had benign morphologic features, and almost always showed enhancement (94 %). MRI of pilocytic astrocytomas typically demonstrated a relatively large, sharply demarcated periventricular mass with pronounced contrast enhancement but minimal or no associated edema. Often, the tumors were cystic on MRI. Despite the well-demarcated appearance grossly and on MRI, pathologic review showed that many of these tumors (64%) infiltrated the surrounding parenchyma, particularly the white matter.
AB - To determine the magnetic resonance imaging (MRI) characteristics of pilocytic astro-cytomas and to correlate them with the histopathologic findings. MRI examinations and histopathologic findings in 56 patients with pilocytic astrocytomas were retrospectively reviewed. In 38 patients, findings on MRI were compared with those on computed tomography. The tumors occurred at all levels of the central nervous system, including the spinal cord. The intracranial tumors were periventricular (73%) or periaqueductal (9%). All tumors were typical pilocytic astrocytomas and were grade 1 on the basis of the World Health Organization classification. At operation, they were often circumscribed and cystic. Radiologically, the tumors were well demarcated (96%), had benign morphologic features, and almost always showed enhancement (94 %). MRI of pilocytic astrocytomas typically demonstrated a relatively large, sharply demarcated periventricular mass with pronounced contrast enhancement but minimal or no associated edema. Often, the tumors were cystic on MRI. Despite the well-demarcated appearance grossly and on MRI, pathologic review showed that many of these tumors (64%) infiltrated the surrounding parenchyma, particularly the white matter.
KW - CECT
KW - CT
KW - MRI
KW - computed tomographic
KW - contrast-enhanced computed tomography
KW - magnetic resonance imaging
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U2 - 10.4065/70.8.747
DO - 10.4065/70.8.747
M3 - Article
C2 - 7630212
AN - SCOPUS:0029144874
SN - 0025-6196
VL - 70
SP - 747
EP - 751
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 8
ER -