Physiology of Cholngiocytes

Anatoliy I. Masyuk; Tatyana V. Masyuk; Nicholas F. LaRusso

doi:10.1016/B978-0-12-809954-4.00044-X

Physiology of Cholngiocytes

Anatoliy I. Masyuk, Tatyana V. Masyuk, Nicholas F. LaRusso

Gastroenterology and Hepatology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

Cholangiocytes are epithelial cells that line the network of interconnecting intrahepatic and extrahepatic bile ducts. The main physiologic function of cholangiocytes is the modification of the bile within the ductal lumen via coordinated bidirectional vectorial transport of ions, solutes, and water. These complex processes are regulated by extracellular signaling molecules, components of bile, and physical forces via various intracellular signaling pathways. The secretory and reabsorptive functions of cholangiocytes and the mechanisms by which these functions are regulated are reviewed in this chapter.

Original language	English (US)
Title of host publication	Physiology of the Gastrointestinal Tract, Sixth Edition
Publisher	Elsevier
Pages	1003-1023
Number of pages	21
Volume	2
ISBN (Electronic)	9780128099544
ISBN (Print)	9780128124260
DOIs	https://doi.org/10.1016/B978-0-12-809954-4.00044-X
State	Published - Jan 1 2018

Keywords

Absorption
Biliary tree
Cholangiocytes
Ductal bile
Intrahepatic and extrahepatic bile ducts
Secretion

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-809954-4.00044-X

Cite this

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title = "Physiology of Cholngiocytes",

abstract = "Cholangiocytes are epithelial cells that line the network of interconnecting intrahepatic and extrahepatic bile ducts. The main physiologic function of cholangiocytes is the modification of the bile within the ductal lumen via coordinated bidirectional vectorial transport of ions, solutes, and water. These complex processes are regulated by extracellular signaling molecules, components of bile, and physical forces via various intracellular signaling pathways. The secretory and reabsorptive functions of cholangiocytes and the mechanisms by which these functions are regulated are reviewed in this chapter.",

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author = "Masyuk, {Anatoliy I.} and Masyuk, {Tatyana V.} and LaRusso, {Nicholas F.}",

year = "2018",

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AU - Masyuk, Anatoliy I.

AU - Masyuk, Tatyana V.

AU - LaRusso, Nicholas F.

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Y1 - 2018/1/1

N2 - Cholangiocytes are epithelial cells that line the network of interconnecting intrahepatic and extrahepatic bile ducts. The main physiologic function of cholangiocytes is the modification of the bile within the ductal lumen via coordinated bidirectional vectorial transport of ions, solutes, and water. These complex processes are regulated by extracellular signaling molecules, components of bile, and physical forces via various intracellular signaling pathways. The secretory and reabsorptive functions of cholangiocytes and the mechanisms by which these functions are regulated are reviewed in this chapter.

AB - Cholangiocytes are epithelial cells that line the network of interconnecting intrahepatic and extrahepatic bile ducts. The main physiologic function of cholangiocytes is the modification of the bile within the ductal lumen via coordinated bidirectional vectorial transport of ions, solutes, and water. These complex processes are regulated by extracellular signaling molecules, components of bile, and physical forces via various intracellular signaling pathways. The secretory and reabsorptive functions of cholangiocytes and the mechanisms by which these functions are regulated are reviewed in this chapter.

KW - Absorption

KW - Biliary tree

KW - Cholangiocytes

KW - Ductal bile

KW - Intrahepatic and extrahepatic bile ducts

KW - Secretion

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M3 - Chapter

AN - SCOPUS:85054416747

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SP - 1003

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BT - Physiology of the Gastrointestinal Tract, Sixth Edition

PB - Elsevier

ER -

Physiology of Cholngiocytes

Abstract

Keywords

ASJC Scopus subject areas

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