Physiology of cholangiocytes

James H. Tabibian, Anatoliy I. Masyuk, Tetyana V. Masyuk, Steven P. O'Hara, Nicholas F La Russo

Research output: Contribution to journalArticle

77 Citations (Scopus)

Abstract

Cholangiocytes are epithelial cells that line the intra- and extrahepatic ducts of the biliary tree. The main physiologic function of cholangiocytes ismodification of hepatocyte-derived bile, an intricate process regulated by hormones, peptides, nucleotides, neurotransmitters, and other molecules through intracellular signaling pathways and cascades. The mechanisms and regulation of bile modification are reviewed herein.

Original languageEnglish (US)
Pages (from-to)541-565
Number of pages25
JournalComprehensive Physiology
Volume3
Issue number1
DOIs
StatePublished - 2013

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Bile
Peptide Hormones
Biliary Tract
Neurotransmitter Agents
Hepatocytes
Nucleotides
Epithelial Cells
Cell Line

ASJC Scopus subject areas

  • Physiology
  • Physiology (medical)

Cite this

Tabibian, J. H., Masyuk, A. I., Masyuk, T. V., O'Hara, S. P., & La Russo, N. F. (2013). Physiology of cholangiocytes. Comprehensive Physiology, 3(1), 541-565. https://doi.org/10.1002/cphy.c120019

Physiology of cholangiocytes. / Tabibian, James H.; Masyuk, Anatoliy I.; Masyuk, Tetyana V.; O'Hara, Steven P.; La Russo, Nicholas F.

In: Comprehensive Physiology, Vol. 3, No. 1, 2013, p. 541-565.

Research output: Contribution to journalArticle

Tabibian, JH, Masyuk, AI, Masyuk, TV, O'Hara, SP & La Russo, NF 2013, 'Physiology of cholangiocytes', Comprehensive Physiology, vol. 3, no. 1, pp. 541-565. https://doi.org/10.1002/cphy.c120019
Tabibian JH, Masyuk AI, Masyuk TV, O'Hara SP, La Russo NF. Physiology of cholangiocytes. Comprehensive Physiology. 2013;3(1):541-565. https://doi.org/10.1002/cphy.c120019
Tabibian, James H. ; Masyuk, Anatoliy I. ; Masyuk, Tetyana V. ; O'Hara, Steven P. ; La Russo, Nicholas F. / Physiology of cholangiocytes. In: Comprehensive Physiology. 2013 ; Vol. 3, No. 1. pp. 541-565.
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