Photoproteins as models of drug receptors

John R. Blinks, David G. Allen, Franklyn G. Prendergast, Gary C. Harrer

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

The calcium-sensitive photoprotein aequorin has properties that make it well suited for studies of protein-ligand interactions. Its behavior resembles that of classical drug receptors in many ways. A two-state model reproduces many of the properties of aequorin, including two that are not consistent with the conventional occupancy model.

Original languageEnglish (US)
Pages (from-to)1237-1244
Number of pages8
JournalLife Sciences
Volume22
Issue number13-15
DOIs
StatePublished - 1978

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ASJC Scopus subject areas

  • Pharmacology

Cite this

Blinks, J. R., Allen, D. G., Prendergast, F. G., & Harrer, G. C. (1978). Photoproteins as models of drug receptors. Life Sciences, 22(13-15), 1237-1244. https://doi.org/10.1016/0024-3205(78)90092-9