TY - JOUR
T1 - Photon-counting detector CT
T2 - System design and clinical applications of an emerging technology
AU - Leng, Shuai
AU - Bruesewitz, Michael
AU - Tao, Shengzhen
AU - Rajendran, Kishore
AU - Halaweish, Ahmed F.
AU - Campeau, Norbert G.
AU - Fletcher, Joel G.
AU - McCollough, Cynthia H.
N1 - Funding Information:
Supported by the National Institutes of Health (EB016966, RR018898).
Publisher Copyright:
© RSNA, 2019.
PY - 2019/5/1
Y1 - 2019/5/1
N2 - Photon-counting detector (PCD) CT is an emerging technology that has shown tremendous progress in the last decade. Various types of PCD CT systems have been developed to investigate the benefits of this technology, which include reduced electronic noise, increased contrast-to-noise ratio with iodinated contrast material and radiation dose efficiency, reduced beam-hardening and metal artifacts, extremely high spatial resolution (33 line pairs per centimeter), simultaneous multienergy data acquisition, and the ability to image with and differentiate among multiple CT contrast agents. PCD technology is described and compared with conventional CT detector technology. With the use of a whole-body research PCD CT system as an example, PCD technology and its use for in vivo high-spatial-resolution multienergy CT imaging is discussed. The potential clinical applications, diagnostic benefits, and challenges associated with this technology are then discussed, and examples with phantom, animal, and patient studies are provided.
AB - Photon-counting detector (PCD) CT is an emerging technology that has shown tremendous progress in the last decade. Various types of PCD CT systems have been developed to investigate the benefits of this technology, which include reduced electronic noise, increased contrast-to-noise ratio with iodinated contrast material and radiation dose efficiency, reduced beam-hardening and metal artifacts, extremely high spatial resolution (33 line pairs per centimeter), simultaneous multienergy data acquisition, and the ability to image with and differentiate among multiple CT contrast agents. PCD technology is described and compared with conventional CT detector technology. With the use of a whole-body research PCD CT system as an example, PCD technology and its use for in vivo high-spatial-resolution multienergy CT imaging is discussed. The potential clinical applications, diagnostic benefits, and challenges associated with this technology are then discussed, and examples with phantom, animal, and patient studies are provided.
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U2 - 10.1148/rg.2019180115
DO - 10.1148/rg.2019180115
M3 - Article
C2 - 31059394
AN - SCOPUS:85065655683
SN - 0271-5333
VL - 39
SP - 729
EP - 743
JO - Radiographics
JF - Radiographics
IS - 3
ER -