Photodynamic therapy of intraductal papillary mucinous neoplasm

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Intraductal papillary mucinous neoplasm (IPMN) of the main pancreatic duct is usually treated by surgical excision of the affected pancreas. Nonoperative ablative therapies have not been described. We treated IPMN of the pancreatic duct with photodynamic therapy (PDT) in a patient who was a poor operative candidate. Porfimer sodium was administered intravenously, and laser light was delivered by a diffusing catheter placed in the pancreatic duct during endoscopic retrograde cholangiopancreatography (ERCP). Imaging and biopsy findings of IPMN resolved after PDT, and symptoms also resolved. Metastatic cancer was diagnosed 2 years after PDT had been initiated. Pancreatic PDT was well tolerated in this case, and may be a therapeutic option for selected patients with IPMN of the main pancreatic duct.

Original languageEnglish (US)
Pages (from-to)213-215
Number of pages3
JournalEndoscopy
Volume44
Issue number2
DOIs
StatePublished - 2012

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Photochemotherapy
Pancreatic Ducts
Neoplasms
Dihematoporphyrin Ether
Endoscopic Retrograde Cholangiopancreatography
Pancreas
Lasers
Catheters
Biopsy
Light
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Photodynamic therapy of intraductal papillary mucinous neoplasm. / Topazian, Mark; Zhong, N.; Baron, T. H.; Vege, Santhi Swaroop; Wang, Kenneth Ke Ning.

In: Endoscopy, Vol. 44, No. 2, 2012, p. 213-215.

Research output: Contribution to journalArticle

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