Abstract
Photodynamic therapy has been used since 1980 at our institution for the management of cancer of the tracheobronchial tree. We identified 13 patients (14 cancers) who were thought to be surgical candidates but who elected to have photodynamic therapy. Thirteen cancers (93 percent) had a complete response to hematoporphyrin-derivative phototherapy. Ten cancers (71 percent) showed a complete response after single treatment, and three (21 percent) required a second course of therapy to achieve a complete response. Ten (77 percent) of 13 cancers have shown no local recurrence. Three patients with persistent cancer underwent surgical resection and were found not to have nodal involvement. We concluded that photodynamic therapy is an alternative to surgical resection in the management of early superficial squamous cell carcinoma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1319-1322 |
| Number of pages | 4 |
| Journal | Chest |
| Volume | 102 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 1992 |
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ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine
Cite this
Photodynamic therapy in the management of early superficial squamous cell carcinoma as an alternative to surgical resection. / Edell, Eric; Cortese, D. A.
In: Chest, Vol. 102, No. 5, 01.01.1992, p. 1319-1322.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Photodynamic therapy in the management of early superficial squamous cell carcinoma as an alternative to surgical resection
AU - Edell, Eric
AU - Cortese, D. A.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - Photodynamic therapy has been used since 1980 at our institution for the management of cancer of the tracheobronchial tree. We identified 13 patients (14 cancers) who were thought to be surgical candidates but who elected to have photodynamic therapy. Thirteen cancers (93 percent) had a complete response to hematoporphyrin-derivative phototherapy. Ten cancers (71 percent) showed a complete response after single treatment, and three (21 percent) required a second course of therapy to achieve a complete response. Ten (77 percent) of 13 cancers have shown no local recurrence. Three patients with persistent cancer underwent surgical resection and were found not to have nodal involvement. We concluded that photodynamic therapy is an alternative to surgical resection in the management of early superficial squamous cell carcinoma.
AB - Photodynamic therapy has been used since 1980 at our institution for the management of cancer of the tracheobronchial tree. We identified 13 patients (14 cancers) who were thought to be surgical candidates but who elected to have photodynamic therapy. Thirteen cancers (93 percent) had a complete response to hematoporphyrin-derivative phototherapy. Ten cancers (71 percent) showed a complete response after single treatment, and three (21 percent) required a second course of therapy to achieve a complete response. Ten (77 percent) of 13 cancers have shown no local recurrence. Three patients with persistent cancer underwent surgical resection and were found not to have nodal involvement. We concluded that photodynamic therapy is an alternative to surgical resection in the management of early superficial squamous cell carcinoma.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026488313&partnerID=8YFLogxK
U2 - 10.1378/chest.102.5.1319
DO - 10.1378/chest.102.5.1319
M3 - Article
C2 - 1424843
AN - SCOPUS:0026488313
VL - 102
SP - 1319
EP - 1322
JO - Chest
JF - Chest
SN - 0012-3692
IS - 5
ER -