Photodynamic therapy for Barrett's esophagus and high grade dysplasia

results of a patient satisfaction survey.

Lois L. Hemminger, Herbert C. Wolfsen

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

There are few data available describing the experience of patients who have undergone photodynamic therapy with porfimer sodium for Barrett's esophagus. We describe the results of a satisfaction survey reported by 16 of 18 patients (11 men, 5 women; median age 75 years; median response at 27 months after treatment) treated with photodynamic therapy for Barrett's esophagus with high-grade dysplasia. Treatments were performed on an outpatient basis although two patients required clinic visits for intravenous fluids. Subjects reported their most significant post-treatment problem was odynophagia or dysphagia (75%), which was best treated with a hydrocodone bitartrate and acetaminophen elixir (75%). Cutaneous photosensitivity persisted for a median of six weeks; two patients had phototoxic reactions requiring clinic evaluation and treatment. All but two patients reported swallowing problems lasting a median of four weeks, and weight loss (median 6.8 kg). All patients indicated they would again choose photodynamic therapy if they were faced with a similar choice of endoscopic treatment versus surgery for Barrett's esophagus with high-grade dysplasia. These results indicate a generally high level of satisfaction in patients who have been treated with porfimer sodium photodynamic therapy for Barrett's esophagus with high-grade dysplasia.

Original languageEnglish (US)
Pages (from-to)139-141
Number of pages3
JournalGastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates
Volume25
Issue number4
StatePublished - Jul 2002

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Barrett Esophagus
Photochemotherapy
Patient Satisfaction
Dihematoporphyrin Ether
Hydrocodone
Therapeutics
Deglutition
Acetaminophen
Ambulatory Care
Deglutition Disorders
Surveys and Questionnaires
Weight Loss
Outpatients
Skin

ASJC Scopus subject areas

  • Gastroenterology
  • Advanced and Specialized Nursing

Cite this

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