Photodynamic therapy and endoscopic metal stent placement for esophageal papillomatosis associated with squamous cell carcinoma

H. C. Wolfsen, L. L. Hemminger, X. J. Geiger, M. Krishna, T. A. Woodward

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Esophageal squamous papillomatosis is a rare condition associated with human papilloma virus infection and has been complicated by the development of squamous cell carcinoma. Photodynamic therapy using porfimer sodium has been used for the treatment of esophageal cancer but has not been utilized in the treatment of esophageal squamous papillomatosis. We report here the first case of papillomatosis and obstructing squamous cell carcinoma of the esophagus palliated with porfimer sodium photodynamic therapy indicating successful photosensitizer uptake in papilloma-laden tissue. Extensive debulking of papilloma and tumor allowed esophageal recanalization and placement of a self-expanding metal stent for long-term dysphagia palliation. This unique case highlights the combined use of endoscopic techniques for optimal treatment results.

Original languageEnglish (US)
Pages (from-to)187-190
Number of pages4
JournalDiseases of the Esophagus
Volume17
Issue number2
DOIs
StatePublished - 2004

Fingerprint

Photochemotherapy
Papilloma
Stents
Squamous Cell Carcinoma
Metals
Dihematoporphyrin Ether
Papillomaviridae
Photosensitizing Agents
Virus Diseases
Esophageal Neoplasms
Deglutition Disorders
Esophagus
Therapeutics
Neoplasms

Keywords

  • Esophageal cancer
  • Papillomatosis
  • Photodynamic therapy
  • Squamous cell carcinoma

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Photodynamic therapy and endoscopic metal stent placement for esophageal papillomatosis associated with squamous cell carcinoma. / Wolfsen, H. C.; Hemminger, L. L.; Geiger, X. J.; Krishna, M.; Woodward, T. A.

In: Diseases of the Esophagus, Vol. 17, No. 2, 2004, p. 187-190.

Research output: Contribution to journalArticle

Wolfsen, H. C. ; Hemminger, L. L. ; Geiger, X. J. ; Krishna, M. ; Woodward, T. A. / Photodynamic therapy and endoscopic metal stent placement for esophageal papillomatosis associated with squamous cell carcinoma. In: Diseases of the Esophagus. 2004 ; Vol. 17, No. 2. pp. 187-190.
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