Twenty-three patients with malignant central nervous system tumors were treated with fludarabine phosphate (2-FAMP) on a 5 day bolus schedule. One brief partial response was observed in 20 malignant astrocytoma patients. 2FAMP as given in this protocol is inactive in previously treated patients with recurrent malignant astrocytomas.
- central nervous system tumors
- fludarabine phosphate
- phase II
ASJC Scopus subject areas
- Pharmacology (medical)