TY - JOUR
T1 - Pharmacogenomics and patient care
T2 - One size does not fit all
AU - Giacomini, Kathleen M.
AU - Yee, Sook Wah
AU - Ratain, Mark J.
AU - Weinshilboum, Richard M.
AU - Kamatani, Naoyuki
AU - Nakamura, Yusuke
PY - 2012/9/26
Y1 - 2012/9/26
N2 - The time is ripe to assess whether pharmacogenomics research - the study of the genetic basis for variation in drug response - has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the f eld and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.
AB - The time is ripe to assess whether pharmacogenomics research - the study of the genetic basis for variation in drug response - has provided important insights into a personalized approach to prescribing and dosing medications. Here, we describe the status of the f eld and approaches for addressing some of the open questions in pharmacogenomics research and use of genetic testing in guiding drug therapy.
UR - http://www.scopus.com/inward/record.url?scp=84866842141&partnerID=8YFLogxK
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U2 - 10.1126/scitranslmed.3003471
DO - 10.1126/scitranslmed.3003471
M3 - Review article
C2 - 23019654
AN - SCOPUS:84866842141
SN - 1946-6234
VL - 4
JO - Science translational medicine
JF - Science translational medicine
IS - 153
M1 - 153ps18
ER -