Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies

Tariq I. Mughal; Naveen Pemmaraju; Rafael Bejar; Robert P. Gale; Prithviraj Bose; Jean Jacques Kiladjian; Josef Prchal; Daniel Royston; Daniel Pollyea; Peter Valent; Tim H. Brümmendorf; Tomasz Skorski; Mrinal Patnaik; Valeria Santini; Pierre Fenaux; Nicole Kucine; Srdan Verstovsek; Ruben Mesa; Tiziano Barbui; Guiseppe Saglio; Richard A. Van Etten

doi:10.1002/hon.2987

Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies

Tariq I. Mughal, Naveen Pemmaraju, Rafael Bejar, Robert P. Gale, Prithviraj Bose, Jean Jacques Kiladjian, Josef Prchal, Daniel Royston, Daniel Pollyea, Peter Valent, Tim H. Brümmendorf, Tomasz Skorski, Mrinal Patnaik, Valeria Santini, Pierre Fenaux, Nicole Kucine, Srdan Verstovsek, Ruben Mesa, Tiziano Barbui, Guiseppe SaglioRichard A. Van Etten

Research output: Contribution to journal › Review article › peer-review

Abstract

Despite much of the past 2 years being engulfed by the devastating consequences of the SAR-CoV-2 pandemic, significant progress, even breathtaking, occurred in the field of chronic myeloid malignancies. Some of this was show-cased at the 15th Post-American Society of Hematology (ASH) and the 25th John Goldman workshops on myeloproliferative neoplasms (MPN) held on 9th-10th December 2020 and 7th-10th October 2021, respectively. The inaugural Post-ASH MPN workshop was set out in 2006 by John Goldman (deceased) and Tariq Mughal to answer emerging translational hematology and therapeutics of patients with these malignancies. Rather than present a resume of the discussions, this perspective focuses on some of the pivotal translational hematology and therapeutic insights in these diseases.

Original language	English (US)
Pages (from-to)	491-504
Number of pages	14
Journal	Hematological Oncology
Volume	40
Issue number	4
DOIs	https://doi.org/10.1002/hon.2987
State	Published - Oct 2022

Keywords

Myelofibrosis
chronic myeloid leukemia
clinical
systemic mastocytosis
thrombosis
translational

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

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10.1002/hon.2987

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Mughal, T. I., Pemmaraju, N., Bejar, R., Gale, R. P., Bose, P., Kiladjian, J. J., Prchal, J., Royston, D., Pollyea, D., Valent, P., Brümmendorf, T. H., Skorski, T., Patnaik, M., Santini, V., Fenaux, P., Kucine, N., Verstovsek, S., Mesa, R., Barbui, T., ... Van Etten, R. A. (2022). Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies. Hematological Oncology, 40(4), 491-504. https://doi.org/10.1002/hon.2987

Mughal, TI, Pemmaraju, N, Bejar, R, Gale, RP, Bose, P, Kiladjian, JJ, Prchal, J, Royston, D, Pollyea, D, Valent, P, Brümmendorf, TH, Skorski, T, Patnaik, M, Santini, V, Fenaux, P, Kucine, N, Verstovsek, S, Mesa, R, Barbui, T, Saglio, G & Van Etten, RA 2022, 'Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies', Hematological Oncology, vol. 40, no. 4, pp. 491-504. https://doi.org/10.1002/hon.2987

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AU - Van Etten, Richard A.

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Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies

Abstract

Keywords

ASJC Scopus subject areas

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