Personalizing immunotherapy: Balancing predictability and precision

Zvia Agur, Stanimir Vuk-Pavlovic

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Despite great expectations and research efforts, anticancer immunotherapy has not yet become a definitive cure. Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of coevolving tumor cells and host immunity. Recent efforts based on a systems-based approach promise improved clinical outcomes engendered by a dynamic modification of personalized therapeutic regimens.

Original languageEnglish (US)
Pages (from-to)1169-1171
Number of pages3
JournalOncoImmunology
Volume1
Issue number7
DOIs
StatePublished - Dec 1 2012

Keywords

  • Clinical trial
  • In-treatment
  • Mathematical model
  • Personalization
  • Prostate cancer

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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