Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model

B. Hu, A. N. Kalloo, S. S C Chung, P. B. Cotton, C. J. Gostout, R. H. Hawes, P. J. Pasricha, N. V. Isakovich, Y. Nakajima, K. Kawashima, Sergey V. Kantsevoy

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Background and study aims: Multiple studies have demonstrated the feasibility of peroral transgastric endoscopic procedures in animal models. The aim of the study was to evaluate the feasibility of a peroral transgastric endoscopic approach to repair abdominal wall hernias. Patients and methods: We performed acute experiments under general anesthesia with endotracheal intubation using 50-kg pigs. Following peroral intubation an incision of the gastric wall was made and the endoscope was advanced into the peritoneal cavity. An internal anterior abdominal wall incision was performed with a needle knife to create an animal model of a ventral hernia. After hernia creation an endoscopic suturing device was used for primary repair of the hernia. After completion of the hernia repair the endoscope was withdrawn into the stomach and the gastric wall incision was closed with endoscopic clips. Then the animals were killed for necropsy. Results: Two acute experiments were performed. Incision of the gastric wall was easily achieved with a needle knife and a pull-type sphincterotome. A large (3 × 2 cm) defect of the abdominal wall (ventral hernia model) was closed with five or six sutures using the endoscopic suturing device. Postmortem examination revealed complete closure of the hernia without any complications. Conclusions: Transgastric endoscopic primary repair of ventral hernias in a porcine model is feasible and may be technically simpler than laparoscopic surgery.

Original languageEnglish (US)
Pages (from-to)390-393
Number of pages4
JournalEndoscopy
Volume39
Issue number5
DOIs
StatePublished - May 2007

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Ventral Hernia
Stomach
Abdominal Wall
Swine
Endoscopes
Herniorrhaphy
Hernia
Needles
Animal Models
Abdominal Hernia
Equipment and Supplies
Intratracheal Intubation
Peritoneal Cavity
Surgical Instruments
Intubation
Laparoscopy
General Anesthesia
Sutures
Autopsy

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

Hu, B., Kalloo, A. N., Chung, S. S. C., Cotton, P. B., Gostout, C. J., Hawes, R. H., ... Kantsevoy, S. V. (2007). Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model. Endoscopy, 39(5), 390-393. https://doi.org/10.1055/s-2007-966426

Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model. / Hu, B.; Kalloo, A. N.; Chung, S. S C; Cotton, P. B.; Gostout, C. J.; Hawes, R. H.; Pasricha, P. J.; Isakovich, N. V.; Nakajima, Y.; Kawashima, K.; Kantsevoy, Sergey V.

In: Endoscopy, Vol. 39, No. 5, 05.2007, p. 390-393.

Research output: Contribution to journalArticle

Hu, B, Kalloo, AN, Chung, SSC, Cotton, PB, Gostout, CJ, Hawes, RH, Pasricha, PJ, Isakovich, NV, Nakajima, Y, Kawashima, K & Kantsevoy, SV 2007, 'Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model', Endoscopy, vol. 39, no. 5, pp. 390-393. https://doi.org/10.1055/s-2007-966426
Hu B, Kalloo AN, Chung SSC, Cotton PB, Gostout CJ, Hawes RH et al. Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model. Endoscopy. 2007 May;39(5):390-393. https://doi.org/10.1055/s-2007-966426
Hu, B. ; Kalloo, A. N. ; Chung, S. S C ; Cotton, P. B. ; Gostout, C. J. ; Hawes, R. H. ; Pasricha, P. J. ; Isakovich, N. V. ; Nakajima, Y. ; Kawashima, K. ; Kantsevoy, Sergey V. / Peroral transgastric endoscopic primary repair of a ventral hernia in a porcine model. In: Endoscopy. 2007 ; Vol. 39, No. 5. pp. 390-393.
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AU - Hawes, R. H.

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