Periprosthetic infections due to Mycobacterium tuberculosis in patients with no prior history of tuberculosis

R. J. Spinner, D. J. Sexton, R. D. Goldner, L. S. Levin

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

Although uncommon, infection of prostheses with Mycobacterium tuberculosis can be managed successfully if it is diagnosed early and treated correctly. A case of M. tuberculosis infection of a prosthetic knee first diagnosed 4.5 years after initial arthroplasty is described. This case and a review of the literature led to the conclusion that there are two distinct patterns of M. tuberculosis infection following joint implant surgery in patients without a history of tuberculosis. (1) Mycobacterium tuberculosis infection may be an unexpected finding at the time of arthroplasty. These patients generally have favorable outcomes using standard antituberculous chemotherapy, without implant removal. (2) Late-onset M. tuberculosis joint infection may be identified in patients with painful, clinically infected, or malfunctioning prostheses. In these cases, medical treatment alone is usually unsuccessful; prosthesis removal is often required. With recent increases in the incidence of tuberculosis in the United States and the emergence of multidrug-resistant strains of M. tuberculosis, periprosthetic tuberculous infection is likely to become more common.

Original languageEnglish (US)
Pages (from-to)217-222
Number of pages6
JournalJournal of Arthroplasty
Volume11
Issue number2
DOIs
StatePublished - 1996
Externally publishedYes

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Mycobacterium tuberculosis
Tuberculosis
Mycobacterium Infections
Infection
Prostheses and Implants
Arthroplasty
Joints
Knee
Drug Therapy
Incidence

Keywords

  • periprosthetic infection
  • tuberculosis

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Periprosthetic infections due to Mycobacterium tuberculosis in patients with no prior history of tuberculosis. / Spinner, R. J.; Sexton, D. J.; Goldner, R. D.; Levin, L. S.

In: Journal of Arthroplasty, Vol. 11, No. 2, 1996, p. 217-222.

Research output: Contribution to journalArticle

Spinner, R. J. ; Sexton, D. J. ; Goldner, R. D. ; Levin, L. S. / Periprosthetic infections due to Mycobacterium tuberculosis in patients with no prior history of tuberculosis. In: Journal of Arthroplasty. 1996 ; Vol. 11, No. 2. pp. 217-222.
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