Peripheral Vascular Disease Involving Transplant Renal Artery

Gurpreet Singh, Neeraj Jolly

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Transplant renal artery stenosis (TRAS) can afflict up-to one-fifth of patients with a transplanted kidney. It is associated with uncontrolled hypertension, loss of precious transplanted organs, and mortality. Pathophysiology, diagnosis, and treatment of TRAS is distinct from vascular diseases of the native kidney. The value of preservation of a transplanted kidney is unique, considering the emotional and surgical stakes involved. This field lacks large randomized trials, and ethically it may never be possible to randomize patients with a solitary transplanted kidney. Therefore, vascular interventionalists have to rely on treating factors that can cause graft malfunction like uncontrolled hypertension and renal ischemia, considering that sufficiently large, prospective, randomized data indicating that treating these factors make a difference may never emerge.

Original languageEnglish (US)
Pages (from-to)E798-E804
JournalThe Journal of invasive cardiology
Volume33
Issue number10
StatePublished - Oct 1 2021

Keywords

  • percutaneous renal interventions
  • renal transplantation
  • transplant renal artery stenosis
  • TRAS

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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