Peripheral T‐cell lymphoma involving the placenta

Paul J. Kurtin, Thomas A. Gaffey, Thomas M. Habermann

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Background. Placental involvement by maternal malignant lymphoma is a rare complication of pregnancy. Methods. The case of a 29‐year‐old woman found to have placental involvement by peripheral T‐cell lymphoma (PTCL) diagnosed by morphologic study, immunoperoxidase stains, and molecular genetic studies is reported. Results. The lymphoma was pathologic Stage IVB and although there were no adverse consequences for the child, but the neoplasm progressed rapidly during the postpartum period. Conclusions. The clinical course suggested that the immunologic changes of the pregnancy exerted a lymphoma‐suppressive effect on the lymphoma. The authors know of no other report of a patient with placental involvement by PTCL.

Original languageEnglish (US)
Pages (from-to)2963-2968
Number of pages6
JournalCancer
Volume70
Issue number12
DOIs
StatePublished - Dec 15 1992

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Keywords

  • T‐cell gene rearrangements
  • malignant lymphoma
  • placenta
  • pregnancy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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