Peripheral nerve conduction studies in galactose-poisoned rats. Demonstration of increased resistance to ischemic conduction associated with endoneurial edema due to sugar alcohol accumulation

P. A. Low, J. D. Schmelzer

Research output: Contribution to journalArticle

26 Scopus citations


Edematous nerves of galactose-poisoned rats had an increased resistance to ischemic conduction block when compared with control animals. Ischemia was caused by cardiac arrest due to intracardiac air embolism in 1 group and by occlusion of the abdominal aorta in another. In these 2 groups of galactose-fed rats, time to 50% conduction block was increased by 27 and 42%, respectively and the difference between control and galactose rats was significant (P < 0.01 and P < 0.001).

Original languageEnglish (US)
Pages (from-to)415-421
Number of pages7
JournalJournal of the neurological sciences
Issue number3
StatePublished - Jun 1983


ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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