Perioperative Anemia: Prevention, Diagnosis, and Management Throughout the Spectrum of Perioperative Care

Matthew A. Warner, Linda Shore-Lesserson, Aryeh Shander, Sephalie Y. Patel, Seth I. Perelman, Nicole R. Guinn

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


Anemia is common in the perioperative period and is associated with poor patient outcomes. Remarkably, anemia is frequently ignored until hemoglobin levels drop low enough to warrant a red blood cell transfusion. This simplified transfusion-based approach has unfortunately shifted clinical focus away from strategies to adequately prevent, diagnose, and treat anemia through direct management of the underlying cause(s). While recommendations have been published for the treatment of anemia before elective surgery, information regarding the design and implementation of evidence-based anemia management strategies is sparse. Moreover, anemia is not solely a concern of the preoperative encounter. Rather, anemia must be actively addressed throughout the perioperative spectrum of patient care. This article provides practical information regarding the implementation of anemia management strategies in surgical patients throughout the perioperative period. This includes evidence-based recommendations for the prevention, diagnosis, and treatment of anemia, including the utility of iron supplementation and erythropoiesis-stimulating agents (ESAs).

Original languageEnglish (US)
Pages (from-to)1364-1380
Number of pages17
JournalAnesthesia and analgesia
Issue number5
StatePublished - May 1 2020

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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