Periodic Hyperammonemic Encephalopathy Associated With a Ureterosigmoidostomy

GREGORY D. CASCINO, JOAN M. JENSEN, LORI A. NELSON, HENRY S. SCHUTTA

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Ureterosigmoidostomy, a urinary diversion procedure performed for treatment of congenital urologic defects or bladder cancer, may be associated with hyperammonemia. A delayed periodic encephalopathy, characterized by dysarthria, ataxia, and coma, developed in a 44-year-old woman who had undergone this procedure. Hyperammonemia-associated neurotoxicity resolved after surgical revision of the ureterosigmoidostomy to a ureteroileostomy. Therefore, a treatable episodic encephalopathy may occur in association with hyperammonemia in patients who have undergone ureterosigmoidostomy.

Original languageEnglish (US)
Pages (from-to)653-656
Number of pages4
JournalMayo Clinic proceedings
Volume64
Issue number6
DOIs
StatePublished - 1989

ASJC Scopus subject areas

  • Medicine(all)

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