Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy

Gregory D Cascino, J. M. Jensen, L. A. Nelson, H. S. Schutta

Research output: Contribution to journalArticle

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Abstract

Ureterosigmoidostomy, a urinary diversion procedure performed for treatment of congenital urologic defects or bladder cancer, may be associated with hyperammonemia. A delayed periodic encephalopathy, characterized by dysarthria, ataxia, and coma, developed in a 44-year-old woman who had undergone this procedure. Hyperammonemia-associated neurotoxicity resolved after surgical revision of the ureterosigmoidostomy to a ureteroileostomy. Therefore, a treatable episodic encephalopathy may occur in association with hyperammonemia in patients who have undergone ureterosigmoidostomy.

Original languageEnglish (US)
Pages (from-to)653-656
Number of pages4
JournalMayo Clinic Proceedings
Volume64
Issue number6
StatePublished - 1989

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Hyperammonemia
Brain Diseases
Urologic Neoplasms
Dysarthria
Urinary Diversion
Ataxia
Coma
Reoperation
Urinary Bladder Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cascino, G. D., Jensen, J. M., Nelson, L. A., & Schutta, H. S. (1989). Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy. Mayo Clinic Proceedings, 64(6), 653-656.

Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy. / Cascino, Gregory D; Jensen, J. M.; Nelson, L. A.; Schutta, H. S.

In: Mayo Clinic Proceedings, Vol. 64, No. 6, 1989, p. 653-656.

Research output: Contribution to journalArticle

Cascino, GD, Jensen, JM, Nelson, LA & Schutta, HS 1989, 'Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy', Mayo Clinic Proceedings, vol. 64, no. 6, pp. 653-656.
Cascino, Gregory D ; Jensen, J. M. ; Nelson, L. A. ; Schutta, H. S. / Periodic hyperammonemic encephalopathy associated with a ureterosigmoidostomy. In: Mayo Clinic Proceedings. 1989 ; Vol. 64, No. 6. pp. 653-656.
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