TY - JOUR
T1 - Peri-procedural myocardial injury
T2 - 2005 Update
AU - Herrmann, Joerg
N1 - Funding Information:
This work was supported at least in part by the Mayo Foundation and the Kellen Foundation. My gratitude to Professor Erbel and Professor Heusch for their mentoring role in this field.
PY - 2005/12
Y1 - 2005/12
N2 - During the past three decades, percutaneous coronary intervention has become one of the cardinal treatment strategies for stenotic coronary artery disease. Technical advances, including the introduction of new devices such as stents, have expanded the interventional capabilities of balloon angioplasty. At the same time, there has been a decline in the rate of major adverse cardiac events, including Q-wave acute myocardial infarction, emergency coronary artery bypass grafting, and cardiac death. Despite these advances, the incidence of post-procedural cardiac marker elevation has not substantially decreased since the first serial assessment 20 years ago. As of now, these post-procedural cardiac marker elevations are considered to represent peri-procedural myocardial injury (PMI) with worse long-term outcome potential. Recent progress has been made for the identification of two main PMI patterns, one near the intervention site (proximal type, PMI type I) and one in the distal perfusion territory of the treated coronary artery (distal type, PMI type II) as well as for preventive strategies. Integrating these new developments into the wealth of clinical information on this topic, this review aims at giving a current perspective on the entity of PMI.
AB - During the past three decades, percutaneous coronary intervention has become one of the cardinal treatment strategies for stenotic coronary artery disease. Technical advances, including the introduction of new devices such as stents, have expanded the interventional capabilities of balloon angioplasty. At the same time, there has been a decline in the rate of major adverse cardiac events, including Q-wave acute myocardial infarction, emergency coronary artery bypass grafting, and cardiac death. Despite these advances, the incidence of post-procedural cardiac marker elevation has not substantially decreased since the first serial assessment 20 years ago. As of now, these post-procedural cardiac marker elevations are considered to represent peri-procedural myocardial injury (PMI) with worse long-term outcome potential. Recent progress has been made for the identification of two main PMI patterns, one near the intervention site (proximal type, PMI type I) and one in the distal perfusion territory of the treated coronary artery (distal type, PMI type II) as well as for preventive strategies. Integrating these new developments into the wealth of clinical information on this topic, this review aims at giving a current perspective on the entity of PMI.
KW - Angioplasty
KW - Atherectomy
KW - Cardiac troponin
KW - Creatine kinase
KW - Embolization
KW - Myocardial infarction
KW - Stents
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U2 - 10.1093/eurheartj/ehi455
DO - 10.1093/eurheartj/ehi455
M3 - Review article
C2 - 16176941
AN - SCOPUS:27944442880
SN - 0195-668X
VL - 26
SP - 2493
EP - 2519
JO - European heart journal
JF - European heart journal
IS - 23
ER -