Peri-ictal SPECT and surgical treatment for intractable epilepsy related to schizencephaly

Gregory D. Cascino, J. R. Buchhalter, J. I. Sirven, E. L. So, J. F. Drazkowski, R. S. Zimmerman, C. Raffel

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The authors evaluated four patients with schizencephaly who underwent subtraction ictal SPECT coregistered to MRI (SISCOM) prior to epilepsy surgery. Three patients had a SISCOM alteration that was concordant with the epileptic brain tissue. Two of these patients were rendered seizure-free and one individual experienced a significant reduction in seizures. The patient with an indeterminate SISCOM had an unfavorable outcome. SISCOM is useful in evaluating patients with schizencephaly for epilepsy surgery.

Original languageEnglish (US)
Pages (from-to)2426-2428
Number of pages3
JournalNeurology
Volume63
Issue number12
DOIs
StatePublished - Dec 28 2004

ASJC Scopus subject areas

  • Clinical Neurology

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