Perfusion-weighted imaging defects during spontaneous migrainous aura

F. Michael Cutrer; A. Gregory Sorensen; Robert M. Weisskoff; Leif Østergaard; Margarita Sanchez Del Rio; E. John Lee; Bruce R. Rosen; Michael A. Moskowitz

doi:10.1002/ana.410430108

Perfusion-weighted imaging defects during spontaneous migrainous aura

F. Michael Cutrer, A. Gregory Sorensen, Robert M. Weisskoff, Leif Østergaard, Margarita Sanchez Del Rio, E. John Lee, Bruce R. Rosen, Michael A. Moskowitz

Neurology

Research output: Contribution to journal › Article › peer-review

309 Scopus citations

Abstract

Perfusion- and diffusion-weighted magnetic resonance imaging was performed during spontaneous visual auras in four migraineurs. Alterations in relative cerebral blood flow (16-53% decrease), cerebral blood volume (6-33% decrease), and tissue mean transit time (10-54% increase) were observed in the gray matter of occipital cortex contralateral to the affected visual hemifield. No changes in the apparent diffusion coefficient were observed either while the patients were symptomatic or after resolution of the visual symptoms but before the onset of headache. Functional magnetic resonance imaging can be a useful noninvasive tool to study hemodynamic changes during spontaneous attacks of migraine with aura.

Original language	English (US)
Pages (from-to)	25-31
Number of pages	7
Journal	Annals of neurology
Volume	43
Issue number	1
DOIs	https://doi.org/10.1002/ana.410430108
State	Published - Jan 1998

ASJC Scopus subject areas

Neurology
Clinical Neurology

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abstract = "Perfusion- and diffusion-weighted magnetic resonance imaging was performed during spontaneous visual auras in four migraineurs. Alterations in relative cerebral blood flow (16-53% decrease), cerebral blood volume (6-33% decrease), and tissue mean transit time (10-54% increase) were observed in the gray matter of occipital cortex contralateral to the affected visual hemifield. No changes in the apparent diffusion coefficient were observed either while the patients were symptomatic or after resolution of the visual symptoms but before the onset of headache. Functional magnetic resonance imaging can be a useful noninvasive tool to study hemodynamic changes during spontaneous attacks of migraine with aura.",

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AU - Cutrer, F. Michael

AU - Sorensen, A. Gregory

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AU - Sanchez Del Rio, Margarita

AU - Lee, E. John

AU - Rosen, Bruce R.

AU - Moskowitz, Michael A.

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Perfusion-weighted imaging defects during spontaneous migrainous aura

Abstract

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