Percutaneous transpedicular biopsy of vertebral body lesions

James S. Jelinek, Mark J. Kransdorf, Richard Gray, Albert J. Aboulafia, Martin M. Malawer

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Study Design. This prospective study evaluates the use of transpedicular biopsy in obtaining diagnostic tissue from vertebral body lesions. Objective. To report the authors' experience of all (N = 32) percutaneous transpedicular biopsies performed between 1990-1994. Summary of Background Data. Previous articles have discussed the value of open biopsy of the vertebral body using a Craig needle. A large series of closed percutaneous transpedicular biopsies have not been reported. Methods. The authors evaluated 32 patients (26 out-patients, six inpatients) who underwent transpedicular biopsy for T1-L4 lesions of the vertebral bodies. None of the tumors had an extraosseous component. Biopsy specimens were obtained from 25 lesions using C-arm fluoroscopy; seven were guided by computed tomography. All biopsies were performed with a 14- to 17-gauge bone biopsy needle. Results. The needle passed through the pedicle into the site of disease in all patients, as confirmed by C-arm fluoroscopy or computed tomography. There were 22 malignancies; four isolated compression fractures, two at T6, one at T7, one at T8; four cases of infection or inflammation; and one case each of Paget's disease and myelofibrosis. Two patients required a second biopsy because the tissue sample was suspicious for lymphoma but not diagnostic. All 26 outpatients were discharged after a 2- hour observation period. There were no complications. Conclusion. Transpedicular biopsy of deep vertebral body lesions using a bone biopsy needle under computed tomography or fluoroscopy guidance can be performed safely and efficaciously as an outpatient procedure.

Original languageEnglish (US)
Pages (from-to)2035-2040
Number of pages6
JournalSpine
Volume21
Issue number17
DOIs
StatePublished - Sep 1 1996
Externally publishedYes

Fingerprint

Biopsy
Fluoroscopy
Outpatients
Tomography
Needle Biopsy
Needles
Compression Fractures
Bone and Bones
Primary Myelofibrosis
Inpatients
Lymphoma
Neoplasms
Observation
Prospective Studies
Inflammation
Infection

Keywords

  • metastasis
  • percutaneous biopsy
  • transpedicular
  • vertebral body

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Orthopedics and Sports Medicine

Cite this

Jelinek, J. S., Kransdorf, M. J., Gray, R., Aboulafia, A. J., & Malawer, M. M. (1996). Percutaneous transpedicular biopsy of vertebral body lesions. Spine, 21(17), 2035-2040. https://doi.org/10.1097/00007632-199609010-00022

Percutaneous transpedicular biopsy of vertebral body lesions. / Jelinek, James S.; Kransdorf, Mark J.; Gray, Richard; Aboulafia, Albert J.; Malawer, Martin M.

In: Spine, Vol. 21, No. 17, 01.09.1996, p. 2035-2040.

Research output: Contribution to journalArticle

Jelinek, JS, Kransdorf, MJ, Gray, R, Aboulafia, AJ & Malawer, MM 1996, 'Percutaneous transpedicular biopsy of vertebral body lesions', Spine, vol. 21, no. 17, pp. 2035-2040. https://doi.org/10.1097/00007632-199609010-00022
Jelinek JS, Kransdorf MJ, Gray R, Aboulafia AJ, Malawer MM. Percutaneous transpedicular biopsy of vertebral body lesions. Spine. 1996 Sep 1;21(17):2035-2040. https://doi.org/10.1097/00007632-199609010-00022
Jelinek, James S. ; Kransdorf, Mark J. ; Gray, Richard ; Aboulafia, Albert J. ; Malawer, Martin M. / Percutaneous transpedicular biopsy of vertebral body lesions. In: Spine. 1996 ; Vol. 21, No. 17. pp. 2035-2040.
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