Pediatric MR elastography of hepatic fibrosis: Principles, technique and early clinical experience

Larry A. Binkovitz, Mounif El-Youssef, Kevin J. Glaser, Meng Yin, Anna K. Binkovitz, Richard Lorne Ehman

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.

Original languageEnglish (US)
Pages (from-to)402-409
Number of pages8
JournalPediatric Radiology
Volume42
Issue number4
DOIs
StatePublished - Apr 2012

Fingerprint

Elasticity Imaging Techniques
Liver Cirrhosis
Fibrosis
Pediatrics
Liver
Biopsy
Therapeutics

Keywords

  • Liver
  • MR elastography
  • MRE
  • Pediatric

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health

Cite this

Pediatric MR elastography of hepatic fibrosis : Principles, technique and early clinical experience. / Binkovitz, Larry A.; El-Youssef, Mounif; Glaser, Kevin J.; Yin, Meng; Binkovitz, Anna K.; Ehman, Richard Lorne.

In: Pediatric Radiology, Vol. 42, No. 4, 04.2012, p. 402-409.

Research output: Contribution to journalArticle

Binkovitz, Larry A. ; El-Youssef, Mounif ; Glaser, Kevin J. ; Yin, Meng ; Binkovitz, Anna K. ; Ehman, Richard Lorne. / Pediatric MR elastography of hepatic fibrosis : Principles, technique and early clinical experience. In: Pediatric Radiology. 2012 ; Vol. 42, No. 4. pp. 402-409.
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