Pediatric MR elastography of hepatic fibrosis: Principles, technique and early clinical experience

Larry A. Binkovitz, Mounif El-Youssef, Kevin J. Glaser, Meng Yin, Anna K. Binkovitz, Richard L. Ehman

Research output: Contribution to journalReview article

29 Scopus citations

Abstract

Numerous pediatric conditions result in hepatic fibrosis. As treatments develop for the underlying disorders, a non-invasive assessment of liver fibrosis would be beneficial as an adjunct or possible replacement for the traditional gold standard, liver biopsy. Magnetic resonance elastography is a noninvasive imaging technique that has been used successfully in adults for identification and assessment of liver fibrosis. This review describes the basic principles of MR elastography as well as the technical aspects specific to children. Clinical pediatric applications, limitations and areas for future research are described.

Original languageEnglish (US)
Pages (from-to)402-409
Number of pages8
JournalPediatric Radiology
Volume42
Issue number4
DOIs
StatePublished - Apr 1 2012

Keywords

  • Liver
  • MR elastography
  • MRE
  • Pediatric

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging

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