Abstract
Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 78-93 |
| Number of pages | 16 |
| Journal | Journal of Pediatric Neurology |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2018 |
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Keywords
- BOLD
- fMRI
- functional
- paradigm
- pediatric
- task-based
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology
Cite this
Pediatric Functional Magnetic Resonance Imaging : Clinical Applications. / Ho, Mai Lan; Welker, Kirk.
In: Journal of Pediatric Neurology, Vol. 16, No. 2, 01.04.2018, p. 78-93.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Pediatric Functional Magnetic Resonance Imaging
T2 - Clinical Applications
AU - Ho, Mai Lan
AU - Welker, Kirk
PY - 2018/4/1
Y1 - 2018/4/1
N2 - Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.
AB - Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.
KW - BOLD
KW - fMRI
KW - functional
KW - paradigm
KW - pediatric
KW - task-based
UR - http://www.scopus.com/inward/record.url?scp=85025669784&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85025669784&partnerID=8YFLogxK
U2 - 10.1055/s-0037-1604216
DO - 10.1055/s-0037-1604216
M3 - Review article
VL - 16
SP - 78
EP - 93
JO - Journal of Pediatric Neurology
JF - Journal of Pediatric Neurology
SN - 1304-2580
IS - 2
ER -