Pediatric Functional Magnetic Resonance Imaging

Clinical Applications

Mai Lan Ho, Kirk Welker

Research output: Contribution to journalReview article

Abstract

Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.

Original languageEnglish (US)
Pages (from-to)78-93
Number of pages16
JournalJournal of Pediatric Neurology
Volume16
Issue number2
DOIs
StatePublished - Apr 1 2018

Fingerprint

Magnetic Resonance Imaging
Pediatrics
Task Performance and Analysis
Language
Psychology
Brain
Population

Keywords

  • BOLD
  • fMRI
  • functional
  • paradigm
  • pediatric
  • task-based

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Cite this

Pediatric Functional Magnetic Resonance Imaging : Clinical Applications. / Ho, Mai Lan; Welker, Kirk.

In: Journal of Pediatric Neurology, Vol. 16, No. 2, 01.04.2018, p. 78-93.

Research output: Contribution to journalReview article

@article{2db02638d8974fa99bb4fb905fdcd1ea,
title = "Pediatric Functional Magnetic Resonance Imaging: Clinical Applications",
abstract = "Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.",
keywords = "BOLD, fMRI, functional, paradigm, pediatric, task-based",
author = "Ho, {Mai Lan} and Kirk Welker",
year = "2018",
month = "4",
day = "1",
doi = "10.1055/s-0037-1604216",
language = "English (US)",
volume = "16",
pages = "78--93",
journal = "Journal of Pediatric Neurology",
issn = "1304-2580",
publisher = "Thieme Medical Publishers",
number = "2",

}

TY - JOUR

T1 - Pediatric Functional Magnetic Resonance Imaging

T2 - Clinical Applications

AU - Ho, Mai Lan

AU - Welker, Kirk

PY - 2018/4/1

Y1 - 2018/4/1

N2 - Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.

AB - Task-based functional magnetic resonance imaging (fMRI) is an imaging technique based on blood oxygenation level-dependent imaging. Maps of brain activation are generated during the performance of designated tasks involving eloquent functions, such as motor, sensory, visual, auditory, and/or language. Optimal performance of fMRI in children requires consideration of multiple psychological and physiological parameters. Also, a solid technical understanding is needed for appropriate study design, implementation, processing, and interpretation. In this article, the authors review the key principles of fMRI technique, study design, data processing, and interpretation. The important clinical applications in the pediatric population will be highlighted, accompanied by example cases from their institution.

KW - BOLD

KW - fMRI

KW - functional

KW - paradigm

KW - pediatric

KW - task-based

UR - http://www.scopus.com/inward/record.url?scp=85025669784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85025669784&partnerID=8YFLogxK

U2 - 10.1055/s-0037-1604216

DO - 10.1055/s-0037-1604216

M3 - Review article

VL - 16

SP - 78

EP - 93

JO - Journal of Pediatric Neurology

JF - Journal of Pediatric Neurology

SN - 1304-2580

IS - 2

ER -