Patterns of failure in primary testicular non-Hodgkin's lymphoma

J. A. Martenson, S. J. Buskirk, D. M. Ilstrup, P. M. Banks, R. G. Evans, J. P. Colgan, J. D. Earle

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Patterns of failure were analyzed in 30 patients with testicular non-Hodgkin's lymphoma: 16 had stage IE disease, ten had stage IIE, and four had stage IV. After orchiectomy, two of the 16 patients with stage IE disease received no additional therapy, one received multiagent chemotherapy, and 13 received pelvic and para-aortic radiation. Twelve patients with stage IE disease had progression, and the median time to progression was 12 months. Of the 14 patients with extratesticular involvement (stage IIE or IV), one (stage IV) received no treatment after orchiectomy, three (stage IIE) received para-aortic and pelvic radiation, and ten (seven stage IIE and three stage IV) received multiagent chemotherapy with or without radiation. Eight of the patients with stage IIE or IV disease had progression, and the median time to progression was 11 months. Widespread extranodal progression was observed in 17 of the 20 patients who had progression. The tendency of testicular lymphoma for early systemic progression suggests a need for multiagent chemotherapy in initial management.

Original languageEnglish (US)
Pages (from-to)297-302
Number of pages6
JournalJournal of Clinical Oncology
Volume6
Issue number2
StatePublished - 1988

Fingerprint

Non-Hodgkin's Lymphoma
Orchiectomy
Radiation
Drug Therapy
Disease Progression
Lymphoma
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Martenson, J. A., Buskirk, S. J., Ilstrup, D. M., Banks, P. M., Evans, R. G., Colgan, J. P., & Earle, J. D. (1988). Patterns of failure in primary testicular non-Hodgkin's lymphoma. Journal of Clinical Oncology, 6(2), 297-302.

Patterns of failure in primary testicular non-Hodgkin's lymphoma. / Martenson, J. A.; Buskirk, S. J.; Ilstrup, D. M.; Banks, P. M.; Evans, R. G.; Colgan, J. P.; Earle, J. D.

In: Journal of Clinical Oncology, Vol. 6, No. 2, 1988, p. 297-302.

Research output: Contribution to journalArticle

Martenson, JA, Buskirk, SJ, Ilstrup, DM, Banks, PM, Evans, RG, Colgan, JP & Earle, JD 1988, 'Patterns of failure in primary testicular non-Hodgkin's lymphoma', Journal of Clinical Oncology, vol. 6, no. 2, pp. 297-302.
Martenson JA, Buskirk SJ, Ilstrup DM, Banks PM, Evans RG, Colgan JP et al. Patterns of failure in primary testicular non-Hodgkin's lymphoma. Journal of Clinical Oncology. 1988;6(2):297-302.
Martenson, J. A. ; Buskirk, S. J. ; Ilstrup, D. M. ; Banks, P. M. ; Evans, R. G. ; Colgan, J. P. ; Earle, J. D. / Patterns of failure in primary testicular non-Hodgkin's lymphoma. In: Journal of Clinical Oncology. 1988 ; Vol. 6, No. 2. pp. 297-302.
@article{7dd7b60bfbe342f8a3127d3dcac7b3b9,
title = "Patterns of failure in primary testicular non-Hodgkin's lymphoma",
abstract = "Patterns of failure were analyzed in 30 patients with testicular non-Hodgkin's lymphoma: 16 had stage IE disease, ten had stage IIE, and four had stage IV. After orchiectomy, two of the 16 patients with stage IE disease received no additional therapy, one received multiagent chemotherapy, and 13 received pelvic and para-aortic radiation. Twelve patients with stage IE disease had progression, and the median time to progression was 12 months. Of the 14 patients with extratesticular involvement (stage IIE or IV), one (stage IV) received no treatment after orchiectomy, three (stage IIE) received para-aortic and pelvic radiation, and ten (seven stage IIE and three stage IV) received multiagent chemotherapy with or without radiation. Eight of the patients with stage IIE or IV disease had progression, and the median time to progression was 11 months. Widespread extranodal progression was observed in 17 of the 20 patients who had progression. The tendency of testicular lymphoma for early systemic progression suggests a need for multiagent chemotherapy in initial management.",
author = "Martenson, {J. A.} and Buskirk, {S. J.} and Ilstrup, {D. M.} and Banks, {P. M.} and Evans, {R. G.} and Colgan, {J. P.} and Earle, {J. D.}",
year = "1988",
language = "English (US)",
volume = "6",
pages = "297--302",
journal = "Journal of Clinical Oncology",
issn = "0732-183X",
publisher = "American Society of Clinical Oncology",
number = "2",

}

TY - JOUR

T1 - Patterns of failure in primary testicular non-Hodgkin's lymphoma

AU - Martenson, J. A.

AU - Buskirk, S. J.

AU - Ilstrup, D. M.

AU - Banks, P. M.

AU - Evans, R. G.

AU - Colgan, J. P.

AU - Earle, J. D.

PY - 1988

Y1 - 1988

N2 - Patterns of failure were analyzed in 30 patients with testicular non-Hodgkin's lymphoma: 16 had stage IE disease, ten had stage IIE, and four had stage IV. After orchiectomy, two of the 16 patients with stage IE disease received no additional therapy, one received multiagent chemotherapy, and 13 received pelvic and para-aortic radiation. Twelve patients with stage IE disease had progression, and the median time to progression was 12 months. Of the 14 patients with extratesticular involvement (stage IIE or IV), one (stage IV) received no treatment after orchiectomy, three (stage IIE) received para-aortic and pelvic radiation, and ten (seven stage IIE and three stage IV) received multiagent chemotherapy with or without radiation. Eight of the patients with stage IIE or IV disease had progression, and the median time to progression was 11 months. Widespread extranodal progression was observed in 17 of the 20 patients who had progression. The tendency of testicular lymphoma for early systemic progression suggests a need for multiagent chemotherapy in initial management.

AB - Patterns of failure were analyzed in 30 patients with testicular non-Hodgkin's lymphoma: 16 had stage IE disease, ten had stage IIE, and four had stage IV. After orchiectomy, two of the 16 patients with stage IE disease received no additional therapy, one received multiagent chemotherapy, and 13 received pelvic and para-aortic radiation. Twelve patients with stage IE disease had progression, and the median time to progression was 12 months. Of the 14 patients with extratesticular involvement (stage IIE or IV), one (stage IV) received no treatment after orchiectomy, three (stage IIE) received para-aortic and pelvic radiation, and ten (seven stage IIE and three stage IV) received multiagent chemotherapy with or without radiation. Eight of the patients with stage IIE or IV disease had progression, and the median time to progression was 11 months. Widespread extranodal progression was observed in 17 of the 20 patients who had progression. The tendency of testicular lymphoma for early systemic progression suggests a need for multiagent chemotherapy in initial management.

UR - http://www.scopus.com/inward/record.url?scp=0023864988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023864988&partnerID=8YFLogxK

M3 - Article

C2 - 3339396

AN - SCOPUS:0023864988

VL - 6

SP - 297

EP - 302

JO - Journal of Clinical Oncology

JF - Journal of Clinical Oncology

SN - 0732-183X

IS - 2

ER -