Patterns of etiology and antibiotic resistance of bacteria causing urinary tract infections in the Anhui Provincial Hospital

Wei Ren, Yuan Fang, Wei Chen, Dennis W Dickson, Hui Xuan Pan, Peng Wang, Lei Lan, Li Jun Ni

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

This study aimed to investigate the distributions and changing trends of pathogens of urinary tract infection in recent years in order to provide a theoretical basis for the rational clinical application of antibiotics. We collected 182 strains of pathogens isolated from patients with urinary tract infection for identification and drug-susceptibility analysis. Among all the pathogens isolated, 107 cases (58.8%) were Escherichia coli, with 100% sensitivity to carbapenems. The gram-positive bacteria exhibited a penicillin resistance rate of up to 90% and a vancomycin sensitive rate of 100%. Among the gram-negative bacteria causing urinary tract infections, the E. coli-produced extended-spectrum beta-lactamase strain exhibited the highest detection rate (49.5%). Currently, E. coli remains the main pathogen of urinary tract infections. The resistance rates of pathogens toward different antibiotics have been increasing, and clinicians should refer to local drug susceptibility test results when choosing the most rational antibiotics.

Original languageEnglish (US)
Pages (from-to)4515-4520
Number of pages6
JournalInternational Journal of Clinical and Experimental Medicine
Volume9
Issue number2
StatePublished - Feb 29 2016

Keywords

  • Antibiotic resistance
  • Etiology
  • Extended-spectrum β-lactamase
  • Urinary tract infection

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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