Patterns of care in the early stages of Alzheimer's disease

Impediments to timely diagnosis

David S Knopman, Jane A. Donohue, Elane M. Gutterman

Research output: Contribution to journalArticle

120 Citations (Scopus)

Abstract

OBJECTIVE: Description of factors associated with delay in diagnosis of Alzheimer's disease (AD). DESIGN: A self-administered mail questionnaire. SETTING: Households including someone with AD identified through a nationwide marketing database. PARTICIPANTS: A total of 1480 caregivers of patients diagnosed with AD. MEASUREMENTS: There were two measures of delay examined through caregiver reports: (1) duration in years from first AD signs until determination of a definite problem, and (2) duration from problem recognition to first physician consultation. Also, caregivers were categorized by time since patient's diagnosis and relationship to patient. Within-group analyses examined the impact of these characteristics on delay measures. RESULTS: Mean lag in years from observation of first symptoms to problem recognition for those diagnosed in the past 12 months, the past 13 to 48 months, and the past 49 months or more was, respectively, 1.20, 1.56, and 2.25 (P <.001). The timing of diagnosis also influenced lag from problem recognition to first physician consultation so that subgroups with recent, less recent, and distant diagnosis reported delays in years of .82, .84, and 1.31 (P <.001). Caregiver relationship was not significantly related to these lags. Correct diagnosis of AD was reported by caregivers in only 38% of cases at initial physician consultation. CONCLUSIONS: These results suggest that both caregivers and physicians lack ready understanding of the difference between memory processes in aging and AD. Ongoing public and professional education is needed to convey the basics of the diagnosis of AD. In addition, routine screening for dementia should be considered to surmount attitudinal and logistical barriers.

Original languageEnglish (US)
Pages (from-to)300-304
Number of pages5
JournalJournal of the American Geriatrics Society
Volume48
Issue number3
StatePublished - Mar 2000
Externally publishedYes

Fingerprint

Alzheimer Disease
Caregivers
Physicians
Referral and Consultation
Professional Education
Postal Service
Marketing
Dementia
Observation
Databases
Recognition (Psychology)

Keywords

  • Alzheimer's disease
  • Assessment
  • Caregivers
  • Dementia
  • Diagnosis

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Patterns of care in the early stages of Alzheimer's disease : Impediments to timely diagnosis. / Knopman, David S; Donohue, Jane A.; Gutterman, Elane M.

In: Journal of the American Geriatrics Society, Vol. 48, No. 3, 03.2000, p. 300-304.

Research output: Contribution to journalArticle

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