Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration

Jeffrey S. Monette, Patrick M. Hutchins, Graziella E. Ronsein, Jake Wimberger, Angela D. Irwin, Chongren Tang, Jaskanwal D. Sara, Baohai Shao, Tomas Vaisar, Amir Lerman, Jay W. Heinecke

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

RATIONALE:: Coronary endothelial dysfunction (ED)–an early marker of atherosclerosis–increases the risk of cardiovascular events. OBJECTIVE:: We tested the hypothesis that cholesterol efflux capacity and HDL particle concentration predict coronary ED better than HDL-cholesterol (HDL-C). METHODS AND RESULTS:: We studied 80 subjects with non-obstructive (

Original languageEnglish (US)
JournalCirculation Research
DOIs
StateAccepted/In press - Apr 29 2016

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HDL Cholesterol
Cholesterol

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Monette, J. S., Hutchins, P. M., Ronsein, G. E., Wimberger, J., Irwin, A. D., Tang, C., ... Heinecke, J. W. (Accepted/In press). Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration. Circulation Research. https://doi.org/10.1161/CIRCRESAHA.116.308357

Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration. / Monette, Jeffrey S.; Hutchins, Patrick M.; Ronsein, Graziella E.; Wimberger, Jake; Irwin, Angela D.; Tang, Chongren; Sara, Jaskanwal D.; Shao, Baohai; Vaisar, Tomas; Lerman, Amir; Heinecke, Jay W.

In: Circulation Research, 29.04.2016.

Research output: Contribution to journalArticle

Monette, Jeffrey S. ; Hutchins, Patrick M. ; Ronsein, Graziella E. ; Wimberger, Jake ; Irwin, Angela D. ; Tang, Chongren ; Sara, Jaskanwal D. ; Shao, Baohai ; Vaisar, Tomas ; Lerman, Amir ; Heinecke, Jay W. / Patients With Coronary Endothelial Dysfunction Have Impaired Cholesterol Efflux Capacity and Reduced HDL Particle Concentration. In: Circulation Research. 2016.
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AU - Irwin, Angela D.

AU - Tang, Chongren

AU - Sara, Jaskanwal D.

AU - Shao, Baohai

AU - Vaisar, Tomas

AU - Lerman, Amir

AU - Heinecke, Jay W.

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