Pathology: What may it tell us?

Claudia F. Lucchinetti; Joseph E. Parisi

Pathology: What may it tell us?

Claudia F. Lucchinetti, Joseph E. Parisi

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) that affects approximately one million people worldwide and is the most common cause of nontraumatic disability in young adults (1). The cardinal features of the MS lesion, namely focal demyelination with relative axonal sparing, inflammation, and gliosis, were described and illustrated over 160 years ago by Carswell (1838), Cruveilher (1841), and Charcot (1868, 1880).

Original language	English (US)
Title of host publication	Handbook of Multiple Sclerosis, Fourth Edition
Publisher	CRC Press
Pages	113-152
Number of pages	40
ISBN (Electronic)	9781420018714
ISBN (Print)	9781574448276
State	Published - Jan 1 2006

ASJC Scopus subject areas

General Medicine
General Neuroscience

Cite this

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title = "Pathology: What may it tell us?",

abstract = "Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) that affects approximately one million people worldwide and is the most common cause of nontraumatic disability in young adults (1). The cardinal features of the MS lesion, namely focal demyelination with relative axonal sparing, inflammation, and gliosis, were described and illustrated over 160 years ago by Carswell (1838), Cruveilher (1841), and Charcot (1868, 1880).",

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AB - Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) that affects approximately one million people worldwide and is the most common cause of nontraumatic disability in young adults (1). The cardinal features of the MS lesion, namely focal demyelination with relative axonal sparing, inflammation, and gliosis, were described and illustrated over 160 years ago by Carswell (1838), Cruveilher (1841), and Charcot (1868, 1880).

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Pathology: What may it tell us?

Abstract

ASJC Scopus subject areas

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