Pathological documentation of complete elimination of Barrett's metaplasia following endoscopic multipolar electrocoagulation therapy

M. B. Fennerty, C. L. Corless, B. Sheppard, Douglas Orrick Faigel, D. A. Lieberman, R. E. Sampliner

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The previous paradigm that Barrett's is an irreversible premalignant lesion has recently been challenged by a proliferation of reports documenting elimination of Barrett's by a variety of endoscopic techniques. Whether Barrett's is entirely eliminated is unknown as endoscopic biopsy samples the surface of the epithelium only. Numerous reports document underlying specialised columnar epithelium in many of these trials. Until now there have been no reports of pathological examination of the entire oesophagus as a specimen. This case documents complete elimination of intestinal metaplasia from the oesophagus and supports the biological plausibility of these research techniques.

Original languageEnglish (US)
Pages (from-to)142-144
Number of pages3
JournalGut
Volume49
Issue number1
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Electrocoagulation
Barrett Esophagus
Documentation
Esophagus
Epithelium
Metaplasia
Research Design
Biopsy
Therapeutics
Intestinal Elimination

Keywords

  • Barrett's oesophagus
  • Endoscopy
  • Multipolar electrocoagulation

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Pathological documentation of complete elimination of Barrett's metaplasia following endoscopic multipolar electrocoagulation therapy. / Fennerty, M. B.; Corless, C. L.; Sheppard, B.; Faigel, Douglas Orrick; Lieberman, D. A.; Sampliner, R. E.

In: Gut, Vol. 49, No. 1, 2001, p. 142-144.

Research output: Contribution to journalArticle

Fennerty, M. B. ; Corless, C. L. ; Sheppard, B. ; Faigel, Douglas Orrick ; Lieberman, D. A. ; Sampliner, R. E. / Pathological documentation of complete elimination of Barrett's metaplasia following endoscopic multipolar electrocoagulation therapy. In: Gut. 2001 ; Vol. 49, No. 1. pp. 142-144.
@article{b830d2e8091c47eea387e7e538a6351a,
title = "Pathological documentation of complete elimination of Barrett's metaplasia following endoscopic multipolar electrocoagulation therapy",
abstract = "The previous paradigm that Barrett's is an irreversible premalignant lesion has recently been challenged by a proliferation of reports documenting elimination of Barrett's by a variety of endoscopic techniques. Whether Barrett's is entirely eliminated is unknown as endoscopic biopsy samples the surface of the epithelium only. Numerous reports document underlying specialised columnar epithelium in many of these trials. Until now there have been no reports of pathological examination of the entire oesophagus as a specimen. This case documents complete elimination of intestinal metaplasia from the oesophagus and supports the biological plausibility of these research techniques.",
keywords = "Barrett's oesophagus, Endoscopy, Multipolar electrocoagulation",
author = "Fennerty, {M. B.} and Corless, {C. L.} and B. Sheppard and Faigel, {Douglas Orrick} and Lieberman, {D. A.} and Sampliner, {R. E.}",
year = "2001",
doi = "10.1136/gut.49.1.142",
language = "English (US)",
volume = "49",
pages = "142--144",
journal = "Gut",
issn = "0017-5749",
publisher = "BMJ Publishing Group",
number = "1",

}

TY - JOUR

T1 - Pathological documentation of complete elimination of Barrett's metaplasia following endoscopic multipolar electrocoagulation therapy

AU - Fennerty, M. B.

AU - Corless, C. L.

AU - Sheppard, B.

AU - Faigel, Douglas Orrick

AU - Lieberman, D. A.

AU - Sampliner, R. E.

PY - 2001

Y1 - 2001

N2 - The previous paradigm that Barrett's is an irreversible premalignant lesion has recently been challenged by a proliferation of reports documenting elimination of Barrett's by a variety of endoscopic techniques. Whether Barrett's is entirely eliminated is unknown as endoscopic biopsy samples the surface of the epithelium only. Numerous reports document underlying specialised columnar epithelium in many of these trials. Until now there have been no reports of pathological examination of the entire oesophagus as a specimen. This case documents complete elimination of intestinal metaplasia from the oesophagus and supports the biological plausibility of these research techniques.

AB - The previous paradigm that Barrett's is an irreversible premalignant lesion has recently been challenged by a proliferation of reports documenting elimination of Barrett's by a variety of endoscopic techniques. Whether Barrett's is entirely eliminated is unknown as endoscopic biopsy samples the surface of the epithelium only. Numerous reports document underlying specialised columnar epithelium in many of these trials. Until now there have been no reports of pathological examination of the entire oesophagus as a specimen. This case documents complete elimination of intestinal metaplasia from the oesophagus and supports the biological plausibility of these research techniques.

KW - Barrett's oesophagus

KW - Endoscopy

KW - Multipolar electrocoagulation

UR - http://www.scopus.com/inward/record.url?scp=0034957228&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034957228&partnerID=8YFLogxK

U2 - 10.1136/gut.49.1.142

DO - 10.1136/gut.49.1.142

M3 - Article

C2 - 11413122

AN - SCOPUS:0034957228

VL - 49

SP - 142

EP - 144

JO - Gut

JF - Gut

SN - 0017-5749

IS - 1

ER -