Patent foramen ovale closure for secondary stroke prevention

Mohamad Alkhouli, Horst Sievert, David R. Holmes

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations

Abstract

Transcatheter closure of patent foramen ovale (PFO) in patients with cryptogenic stroke is gaining momentum after the recent publication of four randomized clinical trials suggesting its benefit. This article provides a contemporary overview of the anatomy and pathophysiology of PFO, the available diagnostic tools for the assessment and risk stratification of PFO, and the current and future landscape of PFO closure devices and their optimal utilization. It also summarizes the current data on PFO closure for stroke prevention, and discusses the remaining open issues in the field of PFO closure.

Original languageEnglish (US)
Pages (from-to)2339-2349
Number of pages11
JournalEuropean heart journal
Volume40
Issue number28
DOIs
StatePublished - Jul 21 2019

Keywords

  • Cryptogenic stroke
  • Device closure
  • Patent foramen ovale
  • Stroke prevention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Patent foramen ovale closure for secondary stroke prevention'. Together they form a unique fingerprint.

Cite this