TY - JOUR
T1 - Parkinson-Related Dementias
AU - Boeve, Bradley F.
N1 - Funding Information:
Dr. Boeve is supported by National Institutes of Health grants P50 AG16574, UO1 AG06786, RO1 AG15866, RO1 AG23195, P50 NS40256, the Alzheimer's Association, and the Robert H. and Clarice Smith and Abigail Van Buren Alzheimer's Disease Research Program of the Mayo Foundation.
PY - 2007/8
Y1 - 2007/8
N2 - Recent advances in neurogenetics, molecular biology, and immunocytochemical staining methods have expanded the spectrum of neurodegenerative disorders now known to cause dementia associated with parkinsonism. This review concentrates on those rare disorders in which cognitive impairment/dementia and parkinsonism coexist: corticobasal syndrome/corticobasal degeneration, progressive supranuclear palsy, multiple system atrophy, and frontotemporal dementia with parkinsonism linked to chromosome 17. The clinical, neuropsychologic, neuroradiologic, and neuropathologic similarities and differences in these disorders are compared and contrasted with each other and with Alzheimer's disease, Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies, highlighting the features critical for identifying the correct diagnosis.
AB - Recent advances in neurogenetics, molecular biology, and immunocytochemical staining methods have expanded the spectrum of neurodegenerative disorders now known to cause dementia associated with parkinsonism. This review concentrates on those rare disorders in which cognitive impairment/dementia and parkinsonism coexist: corticobasal syndrome/corticobasal degeneration, progressive supranuclear palsy, multiple system atrophy, and frontotemporal dementia with parkinsonism linked to chromosome 17. The clinical, neuropsychologic, neuroradiologic, and neuropathologic similarities and differences in these disorders are compared and contrasted with each other and with Alzheimer's disease, Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bodies, highlighting the features critical for identifying the correct diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=34447329558&partnerID=8YFLogxK
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U2 - 10.1016/j.ncl.2007.04.002
DO - 10.1016/j.ncl.2007.04.002
M3 - Review article
C2 - 17659189
AN - SCOPUS:34447329558
SN - 0733-8619
VL - 25
SP - 761
EP - 781
JO - Neurologic clinics
JF - Neurologic clinics
IS - 3
ER -