TY - JOUR
T1 - Parietal Lobe Lesional Epilepsy
T2 - Electroclinical Correlation and Operative Outcome
AU - Cascino, Gregory D.
AU - Hulihan, Joseph F.
AU - Sharbrough, Frank W.
AU - Kelly, Patrick J.
PY - 1993/5
Y1 - 1993/5
N2 - Summary: We retrospectively studied ictal behavior, extracranial EEG, and operative outcome in 10 consecutive patients with intractable partial epilepsy of presumed parietal lobe origin who received a lesionectomy, i.e., resection of the neuroimaging‐identified abnormality, at the Mayo Clinic. Nine patients had a pathologically verified foreign‐tissue lesion, e.g., tumor or vascular malformation, and 1 patient had gliosis. All patients with foreign‐tissue lesions were rendered seizure‐free. The patient with gliosis experienced a reduction in seizure tendency. There were no operative complications. The most common seizure type was a simple partial seizure with visual, motor, or sensory symptoms (n = 8). Complex partial seizures (n = 5) and secondarily generalized tonic‐clonic seizures (GTC, n = 2) were also observed. The ictal behavior was often nonspecific although useful in identifying lateralization of the epileptogenic zone. Extracranial interictal and ictal EEG changes were unreliable markers of the parietal lobe origin of seizure activity. Lesionectomy without chronic intracranial monitoring or functional mapping may be an effective and safe alternative surgical procedure in patients with partial epilepsy related to parietal lobe lesions.
AB - Summary: We retrospectively studied ictal behavior, extracranial EEG, and operative outcome in 10 consecutive patients with intractable partial epilepsy of presumed parietal lobe origin who received a lesionectomy, i.e., resection of the neuroimaging‐identified abnormality, at the Mayo Clinic. Nine patients had a pathologically verified foreign‐tissue lesion, e.g., tumor or vascular malformation, and 1 patient had gliosis. All patients with foreign‐tissue lesions were rendered seizure‐free. The patient with gliosis experienced a reduction in seizure tendency. There were no operative complications. The most common seizure type was a simple partial seizure with visual, motor, or sensory symptoms (n = 8). Complex partial seizures (n = 5) and secondarily generalized tonic‐clonic seizures (GTC, n = 2) were also observed. The ictal behavior was often nonspecific although useful in identifying lateralization of the epileptogenic zone. Extracranial interictal and ictal EEG changes were unreliable markers of the parietal lobe origin of seizure activity. Lesionectomy without chronic intracranial monitoring or functional mapping may be an effective and safe alternative surgical procedure in patients with partial epilepsy related to parietal lobe lesions.
KW - Electroencephalography
KW - Neuroimaging
KW - Neurosurgery
KW - Parietal epilepsy
KW - Parietal lobe
KW - Stereotaxic surgery
UR - http://www.scopus.com/inward/record.url?scp=0027210668&partnerID=8YFLogxK
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U2 - 10.1111/j.1528-1157.1993.tb02591.x
DO - 10.1111/j.1528-1157.1993.tb02591.x
M3 - Article
C2 - 8504784
AN - SCOPUS:0027210668
SN - 0013-9580
VL - 34
SP - 522
EP - 527
JO - Epilepsia
JF - Epilepsia
IS - 3
ER -