Paraneoplastic polymyositis associated with mesothelioma: A brief report

Steven R. Schuster, Brian L. Burnette, Giovanni de Petr, Catherine E. Harmon, John K. Camoriano, Helen J. Ross

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A 77-year-old male with a history of Agent Orange and asbestos exposure and a 22 pack/year history of smoking presented with progressive proximal muscle weakness 8 days after diagnosis of malignant mesothelioma with sarcomatoid features. The clinical diagnosis of paraneoplastic polymyositis was made, and the patient responded to treatment with steroids. Review of the literature shows no previously described association between polymyositis and mesothelioma. We present a discussion of the association of malignancy and inflammatory myopathies, the paraneoplastic syndromes associated with mesothelioma, and the postulated pathophysiology of paraneoplastic inflammatory myopathy.

Original languageEnglish (US)
Pages (from-to)178-180
Number of pages3
JournalCommunity Oncology
Issue number4
StatePublished - Apr 2010

ASJC Scopus subject areas

  • Hematology
  • Oncology


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